BACKGROUND There is widespread concern that the present economic crisis, particularly its effect on unemployment, will adversely affect population health. We investigated how economic changes have affected mortality rates over the past three decades and identified how governments might reduce adverse effects. METHODS We used multivariate regression, correcting for population ageing, past mort...

With the upcoming pervasive deployment of wireless networks and devices on the unlicensed band, co-channel interference caused by frequency collisions among coexisting networks have become one of the major performance limiting challenges. In recent years the coexistence issue has gained increasing attention. However, many collision avoidance schemes are not applicable to multiple frequency hopp...

With the upcoming pervasive deployment of wireless networks and devices on the unlicensed band, co-channel interference caused by frequency collisions among coexisting networks have become one of the major performance limiting challenges. In recent years the coexistence issue has gained increasing attention. However, many collision avoidance schemes are not applicable to multiple frequency hopp...

Background: Gout is a chronic autoinflammatory disease caused by monosodium urate (MSU) crystal deposition [1].Acute gout characterized an acute inflammatory reaction that resolves spontaneously within few days[2], which one of the distinguishing features compared to other arthropathies or self-inflammatory diseases. Autophagy lysosomal degradation pathway essential for cellular growth, surviva...

Ischemic wound complications associated with below-knee amputation (BKA) necessitate conversion to above-knee (AKA) in up 36% of cases. Loss the knee joint has a deleterious impact on rehabilitation, independent living, and health care costs, thus ability promote productive healing BKA flap would be immense value. Cell therapy previously demonstrated pro-angiogenic benefits patients PAD, which ...

Optical-quality microelectromechancal deformable mirrors (DMs) and spatial light modulators (SLMs) are described. With such mirrors, the shape of the reflective surface can be modified dynamically to control an optical wavefront. A principal application is to compensate for aberrations and thereby improve image resolution in telescopes or microscopes: a process known as adaptive optics. iDMs ar...

During heme deficiency in reticulocyte lysates, a translational inhibitor (heme-regulated inhibitor, HRI) that blocks polypeptide chain initiation is activated. HRI is a protein kinase that specifically phosphorylates the 38,000-dalton subunit of the Met-tRNAfMet binding factor, eIF-2. Phosphorylation of eIF-2 by HRI prevents its interaction with at least two additional factors, resulting in a ...

The wealth of genomic data that has recently become available with completion of the sequencing of both the human and a variety of other genomes1 has created a need for rapid and efficient determination of three-dimensional structures of the corresponding proteins. So far, most effort in this so-called structural genomics project has focused on X-ray crystallography, but NMR also shows consider...

In recent years, a number of magic-angle spinning (MAS) solidstate nuclear magnetic resonance (SSNMR) methods have been developed1 for 13C and 15N resonance assignments in uniformly 13C,15N-labeled peptides and proteins.2 The 13CO, 13CR, 13Câ, and amide 15N chemical shifts can be used to estimate the backbone torsion angles φ and ψ.3 Additional constraints on the local structure in U-13C,15N-la...

Statin therapy plays an important role in stabilizing and regressing coronary artery plaques. Omega-3 supplements also have anti-inflammatory antioxidant effects on However, the effect of omega-3 supplementation basis statin stability composition plaques, is still unclear. We searched for randomized controlled trials published prior to November 2020 PubMed, Embase Cochrane databases. Finally, e...