The octyl alcohol, DL-2-ethyl-fl-hexanol, is used industrially as a solvent and, in the form of the ester, di-2-ethylhexyl phthalate, as a plasticizer. According to Shaffer, Carpenter & Smyth (1945) this ester is saponified in rats and rabbits, phthalic acid being excreted and there being also an increase in the short-chain fatty acids in the urine. After feeding the DL-alcohol to rabbits, Akiy...

grinoides ranges from the Canary Islands eastwards across some areas of North Africa, the Middle East and some parts of central Asia (Fergusson-Lees and Christie, 2002). It has characteristic plumage patterns and morphometric differences with respect to the rest of peregrine subspecies, but genetic variation is quite low in the peregrinus/pelegrinoides group, and it could be treated as a subspe...

53 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 216 No. 1 53–63 https://doi.org/10.1083/jcb.20161001

Soluble guanylate cyclases (sGCs) function as heme sensors that selectively bind nitric oxide (NO), triggering reactions essential to animal physiology. Recent discoveries place sGCs in the H-NOX family (heme nitric oxide/oxygen-binding domain), which includes bacterial proteins from aerobic and anaerobic organisms. Some H-NOX proteins tightly bind oxygen (O2), whereas others show no measurable...

To facilitate research in comparative genomics, sequencing projects are increasingly aimed at assembling the genomes of closely related organisms. Given two incomplete assemblies of two related genomes, the question arises how to use the similarity of the two sequences to obtain a better ordering and orientation of both assemblies. In this paper, we formalize this question as the Optimal Synten...

Runoff phosphorus (P) associated with eroded soil contributes to eutrophication to some extent. The present work examines two methods for estimating the potential bioavailability of particulate P (PP) in runoff, and studies the concentrations and losses of different P forms in surface and subsurface runoff from arable soils. The potential bioavailability of PP was approximated by extraction wit...

The vertebrate hypothalamus contains persistent radial glia that have been proposed to function as neural progenitors. In zebrafish, a high level of postembryonic hypothalamic neurogenesis has been observed, but the role of radial glia in generating these new neurons is unclear. We have used inducible Cre-mediated lineage labeling to show that a population of hypothalamic radial glia undergoes ...

Artificial life has now become a mature inter-discipline. In this contribution, its roots are traced, its key questions are raised, its main methodological tools are discussed, and finally its applications are reviewed. As part of the growing body of knowledge at the intersection between the life sciences and computing, artificial life will continue to thrive and benefit from further scientific...

Individuals with REM sleep behaviour disorder are at significantly higher risk of developing Parkinson’s disease. Here we examined visual short-term memory deficits—long associated with Parkinson’s disease—in patients with REM sleep behaviour disorder without Parkinson’s disease using a novel task that measures recall precision. Visual short-term memory for sequentially presented coloured bars ...