Martyna Elas , Jessica M. Magwood , Brandi Butler , Chanel Li , Rona Wardak, Eugene D. Barth , Boris Epel , Samuel Rubinstein , Charles A. Pelizzari, Ralph R. Weichselbaum 1 and Howard J. Halpern Departments of: Radiation and Cellular Oncology and Radiology, University of Chicago Pritzker School of Medicine, Chicago, IL; Center for Electron Paramagnetic Resonance Imaging In Vivo Physiology, Uni...

A method to measure apolipoprotein B radioactivity in whole blood plasma is described that is suitable for routine use in kinetic experiments in vivo. Radiolabeled apolipoprotein B is precipitated from plasma diluted 15- to 30-fold in the presence of carrier low density lipoproteins by 50% isopropanol. The amount of radioiodine in apoB is estimated from the difference between total radioiodine ...

Recent studies suggest that arterial remodeling plays an important role in restenosis and that remodeling at the reference site may also occur. To assess the chronic effect of the reference site remodeling on angioplasty results, we evaluated reference site remodeling in an experimental atherosclerotic restenosis model. Histological sections of iliac stenoses and their associated proximal refer...

To assess the hemodynamic effects of pulmonary microvasculature disruption in emphysema, we examined resting pulmonary hemodynamics and lung function in 12 carefully identified patients with type A chronic obstructive pulmonary disease. Individuals with respiratory muscle weakness and intercurrent infection were excluded. Standard spirometry, helium dilution lung volumes, and single-breath carb...

OBJECTIVE Physical inactivity and increased adiposity contribute to insulin resistance; less is known, however, about the relative contributions of these factors in older adults. The aim of this study was to determine whether cardiovascular fitness, whole-body adiposity, or abdominal adiposity is the strongest predictor of insulin resistance into old age. RESEARCH DESIGN AND METHODS Subjects ...

BACKGROUND Breathlessness is the most common symptom in people with pulmonary arterial hypertension and congenital heart disease (CHD-APAH), previously thought to be caused by worsening PAH, but perhaps also by inflammation and abnormalities of lung function. We studied lung function and airway inflammation in patients with CHD-APAH and compared the results with controls. METHODS AND RESULTS ...

Approximately 6-10,000 upper-extremity amputations are performed each year in the U n i t e d S t a t e s ( 6 , 9 , 1 8 ) . S u c c e s s f u l r e h a b i l i t a t i o n a f t e r u p p e r e x t r e m i t y amputation has significant economic impact both to the amputee and society, since most upper-extremity injuries occur in young working males (5,11). Although the success rates for fingert...