Infants born with ambiguous genitalia pose challenges to medical providers and can cause parental anxiety and distress. Disorders of sexual development (DSD) are classified into 3 major categories (46,XY DSD, 46,XX DSD, and sex chromosome DSD). A thorough history, physical examination, and appropriate diagnostic testing are needed to identify the underlying etiology. An understanding of normal ...

This paper contains a study on how Participatory Design (PD) and distributed software development (DSD) are linked up and whether Distributed Participatory Design is an inherent paradoxon. For this purpose, potential areas of conflict for DSD are identified and two literature surveys of PD and DSD literature have been done.

OBJECTIVES While detrusor-sphincter dyssynergia (DSD) occurs in conjunction with lesions between the brainstem and the sacral cord, it is not well known whether sacral/peripheral lesions contribute to DSD. We studied the relationship between DSD and sacral/peripheral lesions. METHODS One hundred and forty-four patients with diverse neurologic etiologies underwent urodynamic study and analysis...

This chapter addresses a disconnect between two bodies of literature in the ADR field – that relating to “dispute systems design” (DSD) and that relating to “online dispute resolution” (ODR). We show that the need to integrate technology into the ADR field has been understood only in a narrow area and in a limited fashion. To date, technology in dispute resolution has been relegated to the ODR ...

Accurate rain estimation from radar measurements has been a difficult task due to the variation of raindrop size distribution (DSD), lack of accurate axis ratio model, measurement error, clutter, and so forth. Previously, rain estimation from weather radars has been largely dependent upon empirical relations such as R-Z relations. The development of polarimetric radar makes accurate rain DSD re...

Ten years after the consensus meeting on disorders of sex development (DSD), genital surgery continues to raise questions and criticisms concerning its indications, its technical aspects, timing and evaluation. This standpoint details each distinct situation and its possible management in 5 main groups of DSD patients with atypical genitalia: the 46,XX DSD group (congenital adrenal hyperplasia)...

Remarkable progress has been achieved in understanding the mechanisms controlling sex determination, yet the cause for many Disorders of Sex Development (DSD) remains unknown. Of particular interest is a rare XX DSD subtype in which individuals are negative for SRY, the testis determining factor on the Y chromosome, yet develop testes or ovotestes, and both of these phenotypes occur in the same...

The assignment of the sex of rearing for patients with precocious diagnosis of ovotesticular difference of sex development (OT-DSD) is a complex decision. Ovotesticular disorder or difference of sex development (OT-DSD) is a very rare congenital anomaly characterized by the simultaneous presence of both testis and ovary in the same individual. It occurs between 3 and 10% of the total DSD (1). T...

Disorders of Sex Development (DSD) are a heterogeneous group of disorders affecting gonad and/or genito-urinary tract development and usually the endocrine-reproductive system. A genetic diagnosis is made in only around 20% of these cases. The genetic causes of 46,XX-SRY negative testicular DSD as well as ovotesticular DSD are poorly defined. Duplications involving a region located ∼600 kb upst...

In this study the authors evaluate two algorithms, the so-called beta ( ) and constrained methods, proposed for retrieving the governing parameters of the “normalized” gamma drop size distribution (DSD) from dual-polarization radar measurements. The method treats the drop axis ratio as a variable and computes drop shape and DSD parameters from radar reflectivity (ZH), differential reflectivity ...