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Meta-analyses of randomised controlled trials of selective digestive decontamination have clinical outcome measures, mainly pneumonia and mortality. This meta-analysis has a microbiological endpoint and explores the impact of selective digestive decontamination on Gram-negative and Gram-positive carriage and severe infections. We searched electronic databases, Cochrane Register of Controlled Tr...
BACKGROUND Cutaneous leishmanisis (CL) is found worldwide and is considered to be endemic in 88 countries such as Iran. Geographic information system (GIS) is a method that can create, archive, analyze traditional map and place data of the disease distribution. The aim of this study was to produce distributional maps of CL over five years and evaluate the role of GIS in control of CL in Khuzest...
Introduction: Homocysteine is an aminoacid yielded from methionin to cysteine metabolism. Normal plasma concentration of homocysteine in human is between 5-15 mol/l and an increase more than 5 mol/l can increase the risk of cardiovascular diseases, atherosclerosis and thrombosis. On the other hand in dialysis patients due to some reasons such as uremia, genetic factors, dialysis related factors...
Emerging data suggested the efficacy of systemic therapy regimen hepatocellular carcinoma (HCC) is affected by disease etiology. However, robust head-to-head comparative lacking, and it less likely to be examined in prospective manner future. Thus, a network meta-analysis helpful compare different agents based on etiology across trials. We aim evaluate survival advanced HCC patients treated wit...
BACKGROUND The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. METHODS In this double-blind trial, we randomly assigned patients with type 2 diabetes and high cardiovascular risk to receive liraglutide or placebo. The primary composite outcome in the time-to-event analysis was the first oc...
INTRODUCTION Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with virologic suppression. M ethods Cross-sectional data on 5152 (56.92% of the ...
BACKGROUND There is an increasing incidence of type 2 diabetes mellitus (T2DM) in young urban South-Asians. We tested the effect of a pragmatic trimonthly lifestyle modification (LSM) programme (P-LSM) versus a less-intensive 12-monthly control LSM (C-LSM) intervention on a primary composite endpoint of predictors of cardio-metabolic disease (new onset T2DM, hypertension, impaired glucose toler...
(4e) Zumbuehl, A.; Jeannerat, D.; Martin, S.E.; Sohrmann, M.; Stano, P.; Vigassy, T.; Clark, D.D.; Hussey, S.L.; Peter, M.; Peterson, B.R.; Pretsch, E.; Walde, P.; Carreira, E.M. Angew. Chem. Int. Ed. 2004, 43, 5181-5185. (7b) Baginski, M.; Resat, H.; McCammon, J.A. Mol. Pharmacol. 1997, 52, 560-570. (8) (a) McNamara, C.M.; Box, S.; Crawforth, J.M.; Hickman, B.S.; Norwood, T.J.; Rawlings, B.J. ...
This paper investigates the problem of speaker identification and verification in noisy conditions, assuming that speech signals are corrupted by environmental noise but knowledge about the noise characteristics is not available. This research is motivated in part by the potential application of speaker recognition technologies on handheld devices or the Internet. While the technologies promise...
Introduction Many rural development projects and projects are not being evaluated. Therefore, rural developers rarely know their short-term and long-term implications. On the other hand, in order to achieve efficient service and comprehensive coverage of services in all rural areas, emphasis is placed on reaching the hierarchy of rural areas, and to achieve these two objectives, the preparatio...
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