Corresponding author: Nicole Riem, M.D., Department of Anesthesia, St Michael’s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, M5B 1W8, Canada. Tel: 1-416-864-5071, Fax: 1-416-864-6014, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/), ...

AMG 416 (etelcalcetide) is a novel synthetic peptide agonist of the calcium-sensing receptor composed of a linear chain of seven d-amino acids (referred to as the d-amino acid backbone) with a d-cysteine linked to an l-cysteine via a disulfide bond. AMG 416 contains four basic d-arginine residues and is a +4 charged peptide at physiologic pH with a mol. wt. of 1048.3 Da. The pharmacokinetics (P...

Word Count: 197 For: Blood-Vascular Biology *Corresponding author: Jody J. Haigh Mount Sinai Hospital, Samuel Lunenfeld Research Institute 600 University Avenue, Toronto, Ontario Canada M5G 1X5 Telephone: 416-586-8455 Fax: 416-586-8588 e-mail: [email protected] Copyright (c) 2003 American Society of Hematology Blood First Edition Paper, prepublished online October 2, 2003; DOI 10.1182/blood-200...

SUMO MODIFICATION OF NATIVELY UNFOLDED PROTEINS TAU AND α-SYNUCLEIN Véronique Dorval and Paul E. Fraser From the Department of Medical Biophysics and Centre for Research in Neurodegenerative Diseases University of Toronto, Ontario, Canada Running title: Sumoylation of tau and α-synuclein Address correspondence to: Paul E. Fraser, Centre for Research in Neurodegenerative Diseases, University of ...

Zhe-Yi Eye Centre, Hang Zhou, ORBIS, Second Affiliated Hospital of Harbin Medical University, China, LV Prasad Eye Institute, India and Department of Ophthalmology and Vision Sciences, University of Toronto and The Hospital for Sick Children, Canada Correspondence to Dr Agnes M.F. Wong, MD, PhD, FRCSC, Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, 555 Universi...

*Corresponding author. 22 Mailing address: 23 Rm. 449A Dental Research Institute 24 124 Edward Street 25 Toronto, ON M51G6 26 Canada 27 Phone: (416) 979-4917 ext. 4592 28 Fax: (416) 979-4936 29 E-mail: [email protected] 30 AC CE P ED Copyright © 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.01161-06...

INTRODUCTION .......................................................................................................................................................414 NFB AND REGULATION OF THE IMMUNE SYSTEM ................................................................................415 Proand Antiapoptotic Functions of NFB ......................................................................

AFFILIATIONS: Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada Division of Haematology/Oncology, Department of Paediatrics, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada Pediatric Hematology and Oncology, Johann-Wolfgang Goethe-University Hospital, Frankfurt, Germany ADDRESS FOR ...

. clicking here colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others . here following the guidelines can be obtained by Permission to republish or repurpose articles or portions of articles (this information is current as of July 27, 2010 ): The following resources related to this article are available online at www.s...

Abstract Introduction Oral appliance therapy device quality is an important factor for successful, efficient treatment of Obstructive Sleep Apnea. Poor quality, defined in this investigation as the remake rate, costly. A previous reports that 13% oral devices required remakes, each costing estimated $300 lost productivity, fees and three weeks therapy. Other investigations associate poor with e...