In the cooperative study AML-IGCI-84 27 children with AML (FAB M1 7X, M2 4X, M3 1X, M4 6X and M5 8X; 1 megakaryocytic leukemia) have been treated. The median initial white blood cell count was 18.0 G/l (range 1.8-1,350.0 G/l). 1 or 2 courses of induction therapy were used: I1 (aclacinomycin-A (ACLA-A), VP-16 and ARA-C) and I2 (daunorubicin (DNR), VP-16, and ARA-C). I2 was used only if bone marr...

A laboratory experiment was conducted to determine hexavalent chromium (Cr) accumulation in the mullet and investigate Cr toxicity using a panel of biomarkers including metallothioneins (MTs), glutathione (GSH), glutathione S-transferase (GST), and superoxide dismutases (SODs) for 4 weeks. Cr bioaccumulation in all tissues, except muscle, was consistently timeand dose-dependent. The accumulatio...

We report what we believe to be the first demonstration of a room-temperature, continuous-wave Cr(4+):Y(3)Al(5)O(12) (Cr(4+):YAG) double-clad crystal fiber laser grown by the codrawing laser heated pedestal growth method. The threshold is below 100 mW, which is a factor of 4 lower than previously reported Cr(4+)-doped lasers. A slope efficiency of 6.9% was obtained, and is in good agreement wit...

Efficient access to a large chemical space based on new scaffolds with defined 3D conformations and highly variable in the side chains is needed to find novel functional materials. Four heterocyclic scaffolds based on a four component Ugi reaction of α-amino acids, oxo components, isocyanides and primary or secondary amines suitably functionalized are described. A handful of examples are descri...

The activation of the ethene tetramerisation catalyst system based upon [CrCl3(THF)3] and N( Pr)(PPh2)2 has been investigated in situ via the reaction of [CrCl3{PPh2N(R)PPh2}(THF)] 1a (R = Pr) with excess AlMe3 in toluene. The Cr K-edge XAFS spectrum of the solution freeze quenched after 1 min reaction time indicated monomethylation of the metal with the resultant product being [CrClMe(ClAlCl3)...

To determine the metabolite ratios of (Cho + Cr)/Cit and (Cho + Cr)/Spm in patients with two ranges of pathological Gleason scores, namely (3 + 4) and (4 + 3). By using the localized two-dimensional (2D) J-resolved spectroscopy (JPRESS) technique, the metabolites ratios can be calculated and correlated with prostate cancer aggressiveness. A total of 24 patients who underwent endorectal 2D JPRES...

The unit cell of the title compound, poly[[μ-aqua-μ-hydroxido-di-μ-oxalato-chromium(III)disodium] monohydrate], {[CrNa(2)(C(2)O(4))(2)(OH)(H(2)O)]·H(2)O}(n), contains four [Na1(μ-H(2)O)Na2][(C(2)O(4))(2)Cr(μ-OH)·H(2)O] formula units, each of which consists of two crystallographically independent Na(+) sites (bridged by one aqua ligand), one half of a centrosymmetric di-μ-hydroxido-bis-[cis-bis-...

operated stably after more than 500h. In conclusion, we obtained a nearly round FFP in the 650nm band wavelength using the S3-laser. The laser had good I-L characteristics and good reliability at lOmW and 60°C. We consider that the laser could be of use as a light source in optical disk systems. and TERAMOTO, I.: 'Novel technology for formation of a narrow active layer in buried heterostructure...

Clean-up of wastewaters with coexisting heavy metals and organic contaminants is a huge issue worldwide. In this study, a novel anatase/titanate nanosheet composite material (labeled as TNS) synthesized through a one-step hydrothermal reaction was demonstrated to achieve the goal of simultaneous removal of Cr(VI) and 4-cholophenol (4-CP) from water. TEM and XRD analyses indicated the TNS was a ...