This paper presents a framework for the calculation of functional requirements at several stages of the product life cycle. It uses the TTRS/MGRE concept for the determination of dimension chains. The geometry of the assembly is represented using a parametric model constituted of points and vectors. Finally, it also integrates the calculation of part deformation due to changing operating condit...

Relationships between student approaches to learning and learning outcomes were explored in a population of fi rst year students studying anatomy in a medical program off ered by a research intensive Australian university. An online survey version of the Study Process Questionnaire (Biggs et al, 2001), examination scripts and student results were the source data for this study. Th ese students ...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365 1. Evidence of Cardiac Fatigue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 367 1.1 During Prolonged Exercise . . . . . . . . . . . . . . . . . . . ...

Deregulated microRNAs participate in carcinogenesis and cancer progression, but their roles in cancer development remain unclear. In this study, miR-365 expression was found to be downregulated in human colon cancer tissues as compared with that in matched non-neoplastic mucosa tissues, and its downregulation was correlated with cancer progression and poor survival in colon cancer patients. Fun...

OBJECTIVE This study aims to investigate the role and mechanism of miR-365 in the coronary atherosclerosis (AS). PATIENTS AND METHODS Blood were collected from AS patients and healthy people, coronary plaque and adjacent arterial tissue were collected from AS patients. QRT-PCR method was used to detect expressions of miR-365 and IL-6 in coronary plaque, blood monocytes, and serum. Western blo...