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We reported recently that regulation by intracellular pH (pH(i)) of the murine Cl-/HCO(3)(-) exchanger AE2 requires amino acid residues 310-347 of the polypeptide's NH(2)-terminal cytoplasmic domain. We have now identified individual amino acid residues within this region whose integrity is required for regulation of AE2 by pH. 36Cl- efflux from AE2-expressing Xenopus oocytes was monitored duri...

Computing based on biochemical processes is a newest rapidly developing field of unconventional information and signal processing. In this paper we present results of our research in the field of biochemical computing and summarize the obtained numerical and experimental data for implementations of the standard two-input OR and AND gates with double-sigmoid shape of the output signal. This form...

Selective deuterium substitution as a means of ameliorating clinically relevant pharmacokinetic drug interactions is demonstrated in this study. Carbon-deuterium bonds are more stable than corresponding carbon-hydrogen bonds. Using a precision deuteration platform, the two hydrogen atoms at the methylenedioxy carbon of paroxetine were substituted with deuterium. The new chemical entity, CTP-347...

PURPOSE To evaluate the clinical characteristics and outcomes of cataract surgery in highly myopic Korean subjects. METHODS We retrospectively reviewed the medical records of 694 eyes of 694 patients who underwent cataract surgery. The case group included 347 eyes of 347 patients whose axial lengths (AXL) were ≥26.00 mm, and the control group included 347 eyes of 347 patients with AXL between...

[This corrects the article on p. 347 in vol. 3, PMID: 23087675.].

[This corrects the article on p. 347 in vol. 41, PMID: 28758071.].

Genetic variation in Scandinavian brown trout (Salmo trutta L.): evidence of distinct sympatric populations" (1976). Biological Sciences Faculty Publications. 347.