Down-regulation of the miRNA miR-338-3p correlates with the invasive ability of hepatocellular carcinoma (HCC) cells. However, it is currently unclear whether down-regulation of miR-338-3p induces epithelial-mesenchymal transition (EMT), which may be the underlying mechanism governing HCC invasion. Here, we demonstrate that restoration of miR-338-3p expression via transfection of a miR-338-3p m...

Hepatitis B virus X protein (HBx) is recognized as an oncogene in hepatocellular carcinoma (HCC). HBx regulates microRNA expression, including down-regulating miR-338-3p in LO2 cells. Here, we investigated miR-338-3p function in HBx-mediated hepatocarcinogenesis. In 23 HBV-infected HCC clinical patient tumor and adjacent non-tumor control tissues, 17 and 19 tumors expressed HBx mRNA and protein...

Tall fescue (Schedonorus arundinaceus (Schreb.) Dumort.) is the most widely used species in European transition zone, however, despite its good wear tolerance, use still limited to lawns and landscape areas due concerns about ability withstand low mowing regimes. A two years field study was conducted access performance of twenty tall cultivars (‘Ares’, ‘Armani’, ‘Dynamites LS’, ‘Firecracker SLS...

to study the effect of different harvesting intensity on forage production of bromus tomentellus was considered of majid abad qorveh. treatments included four harvested intensity 25, 50 and 75 percent and control (no harvest).data were analyzed based on splitplot over time during four years(1386-1389) using sas and irristat software. the results showed that the main effect of year, different ha...

Zeria Pharmaceutical Co., Ltd. (Headquarters: Chuo-ku, Tokyo; President and CEO: Sachiaki Ibe; “Zeria”) and Astellas Pharma Inc. (Headquarters: Chuo-ku, Tokyo; President and CEO: Masafumi Nogimori; “Astellas Pharma”) announced today that Zeria had submitted the application for marketing approval of the therapeutic agent (nonproprietary name: acotiamide hydrochloride hydrate; “acotiamide”; Zeria...

in order to study of use advantage in the intercropping system fennel (foeniculum vulgare mill) and fenugreek (trigonella foenum-graecum l) in different ratios of intercropping and sole cropping, an experiment with use replacement and additive intercropping based on randomized complete block design with three replications was conducted at the research station of faculty of agriculture, universi...

In order to determine the extent and frequency of such events, ten fourth-year Doctor of Pharmacy candidates used a method of documentation to quantify their clinical interventions during two weeks each of three of four selected advanced pharmacy practice experiences between July 1997 and March 1998. Encounters (338) were documented and data collected at 27 clerkship sites. At least 64 percent ...

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BACKGROUND MicroRNAs (miRNA) have been documented playing a critical role in cancer progression. Although miR-338-3p has been implicated in several cancers, its role in gastric cancer is still unknown. The aim of our study was to investigate the role of miR-338-3p in gastric cancer progression. METHODS Expression levels of miR-338-3p in gastric cancer cell lines and tissues were determined by...

Insect larvae and adult insects found on human corpses can provide important forensic evidence however it is useful to be able to prove evidence of association. Without this, it could be claimed that the insect evidence was a contaminant or had been planted on the body. This paper describes how mitochondrial DNA (mtDNA) and STR analysis of the crop contents of larvae of the blowfly Aldrichina g...