نتایج جستجو برای: 311
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INTRODUCTION A novel amyloid β (Aβ) synthetic peptide vaccine (UB-311) has been evaluated in a first-in-human trial with patients of mild-to-moderate Alzheimer's disease. We describe translational research covering vaccine design, preclinical characterization, and phase-I clinical trial with supportive outcome that advances UB-311 into an ongoing phase-II trial. METHODS UB-311 is constructed ...
We perform total-energy calculations based on the tight-binding Hamiltonian scheme ~i! to study the structural properties and energetics of the extended $311% defects depending upon their dimensions and interstitial concentrations and ~ii! to find possible mechanisms of interstitial capture by and release from the $311% defects. The generalized orbital-based linear-scaling method implemented on...
P-type GaAs/AlAs distributed Bragg mirrors have been grown using molecular beam epitaxy on (100) and (311)A GaAs substrates in a similar conditions. A comparison of I-V measurements shows that the resistance of the ungraded mirrors grown on the (311)A substrate is 35 times lower than those grown on the (100) substrate with similar structure. The effective barrier heights for both (311 )A and (1...
Amorphization of a n-type Czochralski wafer was achieved using a series of Si implants of 30 and 120 keV, each at a dose of 1310 cm. The Si implants produced a 2400 Å deep amorphous layer, which was then implanted with 4 keV 1310/cm B. Postimplantation anneals were performed in a tube furnace at 750 °C, for times ranging from 15 min to 6 h. Secondary ion mass spectrometry was used to monitor th...
Comparative study on InAs/InGaAs dots-in-a-well structure grown on GaAs(311) B and (100) substrates.
The InAs/InGaAs dots-in-a-well (DWELL) structures were grown on both GaAs(311) B and (100) substrates by molecular beam epitaxy. Quantum dots (QDs) grown on GaAs(311) B substrate are of higher density and more uniform size distribution, yet QDs grown on GaAs(100) substrate demonstrate a bimodal size distribution. The growth mechanism of these surface morphologies was briefly discussed. We found...
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