OBJECTIVE To determine the optimal methotrexate dose in individual patients and to explore whether this optimal dose and the level of disease activity at that dose could be predicted. METHODS Data from CAMERA II trial comparing MTX and MTX with 10 mg of prednisone both in a tight control treatment strategy in early RA was used. For each patient a curve for disease activity over time was fitte...

Two studies were conducted during which 23 patients with chronic migraine were exposed to pulsing electromagnetic fields over the inner thigh. In an open study, 11 subjects kept a 2-week headache log before and after 2 to 3 weeks of exposure to pulsing electromagnetic fields for 1 hour per day, 5 days per week. The number of headaches per week decreased from 4.03 during the baseline period to 0...

This study qualitatively examined an 8-week group exercise and counseling intervention for breast and prostate cancer survivors. Groups exercised 3 days per week, 50 minutes per session, performing moderate-intensity aerobic and resistance training. Groups also underwent 90-minute supportive group psychotherapy sessions once per week. Survivors discussed their experiences in focus groups post i...

Davis, D.S., P.E. Ashby, K.L. McCale, J.A. McQuain, and J.M. Wine. The effectiveness of 3 stretching techniques on hamstring flexibility using consistent stretching parameters. J. Strength Cond. Res. 19(1):27–32. 2005.—This study compares the effects of 3 common stretching techniques on the length of the hamstring muscle group during a 4-week training program. Subjects were 19 young adults betw...

the purpose of this study was to investigate the interference effect of concurrent strength and endurance training on maximum strength and vo2max in non-athletes. for this purpose, 34 sedentary healthy men (mean age 22±1.18 years, height 173.61±6.48 cm, and weight 56.13±8.50 kg) voluntarily participated in this study. initially, subjects were randomly assigned to one of four training groups: st...

allergic rhinitis is the most common cause of allergic diseases. the recent guidelines of allergic rhinitis and its impact on asthma (aria) group, classified it to intermittent (less than 4 days per week and for less than 4 weeks) and persistent (more than 4 days per week or lasting more than 4 weeks regardless of the number of days per week). the present study evaluates the patients with aria ...