introduction: antimicrobial peptides as the body's defense strategy play an important role in resistance against infection of microorganism. these peptides are able to modulate the immune and inflammatory processes through the production of defensive molecules. therefore, the modulatory effects of brevinin-2r, an antimicrobial peptide extracted from the skin of the frog (rana ridibunda), w...

Soluble interleukin 2 receptor (sIL-2R) levels reflect mononuclear cell activation and are elevated in a variety of autoimmune, neoplastic and infectious conditions. Several investigators have studied sIL-2R levels in patients with Type I diabetes mellitus (IDDM), but results have been conflicting. Our primary objective in this study was to compare sIL-2R levels of children and adolescents with...

Activation of T lymphocytes leads to the expression of interleukin-2 receptors (IL-2R) on the cell surface (1) as well as the release of soluble IL-2R (sIL-2R) molecules into the circulation (2). T lymphocytes are the predominant IL-2R bearing cells (3) and hence serum sIL-2R level provides a satisfactory indicator of T-cell activation in vivo. Elevated serum levels of sIL-2R have been reported...

The aim of this study was to assess the factorial structure of the Brazilian version of CSAI-2, using several structures suggested in previous studies. Two samples consisted of Brazilian soccer players, 266 from regional level (age 22.87 +/- 4.08 years; athletic experience 11.32 +/- 4.15 years) and 263 from national level (age 23.16 +/- 4.37 years; athletic experience 11.11 +/- 4.78 years) were...

IL-2 is a cytokine that functions as a growth factor and central regulator in the immune system and mediates its effects through ligand-induced hetero-trimerization of the receptor subunits IL-2R alpha, IL-2R beta, and gamma(c). Here, we describe the crystal structure of the trimeric assembly of the human IL-2 receptor ectodomains in complex with IL-2 at 3.0 A resolution. The quaternary structu...

The primary aim of the paper is to conduct research on personality traits and pre-competition anxiety Esports sports players, in addition confirming differences between two examined groups. has been conducted 67 (N=67) subjects, 30 whom are semi-professional or professional gamers who participate state-level regional-level competitions. remaining 37 subjects highest-ranked athletes Bosnia Herze...

The multidimensional approach to the study of anxiety (Martens, Vealey, & Burton, 1990a) considers subcomponents of anxiety, specifically cognitive anxiety, somatic anxiety, and self-confidence. Much of the research based on this theory has utilized the Competitive State Anxiety Inventory (CSAI-2) (Martens, Burton, Vealey, Bump, & Smith, 1990b). Findings have been inconsistent, with some resear...

A system for the detection of soluble IL-2R by sandwich enzyme linked immunosorbent assay (ELISA) was established. This assay system has good reproducibility, and was found to be specific for soluble IL-2R by examination of the binding of anti-IgM antibody or anti-IL-2R monoclonal antibody (mAb) with IgM or soluble IL-2R and inhibition by IL-2 of the binding of anti-IL-2R mAb to soluble IL-2R. ...

and Applied Analysis 3 2. Lemmas In order to establish our main results we need two inequalities, which we present in this section. Lemma 2.1. If r ∈ 0, 1 , then g t − [ t2 t 1 2r /3 1 − 2r ( t 1 2r /3 1 t )] log t 1 − r ( t 1 2r /3 2 − t 1 2r /3 t2 − 1 ) > 0 2.1 for t ∈ 1, ∞ . Proof. Let p 1 2r /3, g1 t t1−pg ′ t , g2 t tg ′ 1 t , g3 t t 1−pg ′ 2 t , g4 t t g ′ 3 t , g5 t t3−pg ′ 4 t , g6 t t ...

In the title compound, [RuCl(2)(C(16)H(32)P(2))(2)], the Ru(II) ion is situated on a twofold rotation axis, so the asymmetric unit contains one half-mol-ecule. The slightly distorted octa-hedral environment of the Ru center is formed by four P atoms [Ru-P = 2.4417 (6) and 2.4544 (6) Å] from two different (1S,1S',2R,2R')-TangPhos ligands [(1S,1S',2R,2R')-TangPhos = (1S,1S',2R,2R')-(+)-1,1'-di-te...