نتایج جستجو برای: 28a
تعداد نتایج: 295 فیلتر نتایج به سال:
OBJECTIVE To demonstrate the inhibitory function of the prodomain of tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE) on TACE activity and to develop an approach to interfere with inflammation processes. METHODS The cDNA encoding the full-length ectodomain (T1300) and prodomain (T591) of TACE were amplified by RT-PCR. The expression plasmids (pET-28a (+)-T1300 and pET-28a (+)-...
The lambda interferons (IL-28a, 28b, and IL-29) inhibit the replication of many viruses, but their role in the inhibition of HIV-1 infection remains unclear. During this study, we monitored IL-29 production in HIV-1 infected individuals and analyzed the in vitro and in vivo inhibition of HIV-1 production. Prior treatment with IL-28a or IL-29 induced an antiviral state in cultured primary T-cell...
• Structural elucidation of two pneumococcal capsular polysaccharides (CPS) Comparison CPS structures and biosynthesis between serotype 28 F, 28A 16 F Correlation with supported proposed function glycosyltransferase Latex agglutination revealed the importance O Ac PO 4 in serological reaction Capsular are key virulent factors pathogenesis Streptococcus pneumoniae . The previously unknown 28F we...
Lynch syndrome is a hereditary cancer syndrome caused by a constitutional mutation in one of the mismatch repair genes. The implementation of predictive testing and targeted preventative surveillance is hindered by the frequent finding of sequence variants of uncertain significance in these genes. We aimed to determine the pathogenicity of previously reported variants (c.-28A>G and c.-7C>T) wit...
Long non-coding RNAs are emerging to be novel regulators in gene expression. In current study, lncRNAs microarray and lncRNA-mRNA co-expression analysis were performed to explore the alternation and function of lncRNAs in cervical cancer cells. We identified that 4750 lncRNAs (15.52%) were differentially expressed in SiHa (HPV-16 positive) (2127 up-regulated and 2623 down-regulated) compared wi...
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