نتایج جستجو برای: 23 dihydroquinazolin 41h one
تعداد نتایج: 2142919 فیلتر نتایج به سال:
In search of potent inhibitors cholinesterase enzymes and antioxidant agents, synthetic derivatives dihydroquinazolin-4(1H)-one 1-38 were evaluated as potential anti-Alzheimer agents through in vitro acetylcholinesterase (AChE) butyrylcholinesterase (BChE) inhibitions radical (DPPH ABTS) scavenging activities. The (SAR) was mainly based on the different substituents at aryl part which showed a ...
Introduction: By development of bacterial drug-resistance to traditional antibacterial drugs and fungal infections, the need to design, synthesis, and use of new and effective antibacterial and antifungal drugs is increased. Quinazolinone derivatives are heterocyclic compounds with nitrogen atoms that have pharmacological properties such as anti-bacterial, anti-tumor, anti-inflammatory and an...
Synthesis of the title compound from 4-methoxyaniline was accomplished in three steps. The structure was supported by spectroscopic data and unambiguously confirmed by single crystal X-ray diffraction data. It crystallizes in the monoclinic space group P21 with unit cell dimensions a = 9.9349(8), b = 6.3377(5), c = 10.5783(10) Å, β = 97.752(3)°, V = 659.97(10) Å, Z = 2.
A novel type of 2-(un)substituted phenyl-2,3-dihydroquinazolin-4(1H)-one (DQL) derivatives were designed and synthesized to study the impact of halogen substituents on interactions between DQL and human serum albumin (HSA) by comparison methodology. The interactions between DQL and HSA were studied by fluorescence spectroscopy. The intrinsic fluorescence of human serum albumin was quenched by D...
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