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The recent advances in the understanding of psoriasis pathogenesis have clarified the pivotal role of interleukin (IL)-23. It is a heterodimeric cytokine consisting of two subunits, the unique p19 and the p40, which are shared with IL-12. The basic role of IL-23 in psoriasis is the activation and maintenance of the T-helper 17 pathway. New research findings indicate that IL-23 is more important...
A series of Er3+/Tm3+ co-doped fluoride (ZBLAN) glasses and fibers was prepared and their fluorescence spectra was measured under excitation at 793 nm and 980 nm. Correlation between the self-absorption effect of rare-earth ions and the shift of the emission peak was investigated. With the increasing length of fiber, the emission peaks red-shift when self-absorption occurs at the upper level of...
INTRODUCTION.............................................................. 793 TWORrS DISCOVERY ......... ............................ 794 D'HERELLE'S DISCOVERY ............... ...................... 795 THE DISCOVERY OF TWORTS DISCOVERY ............................... 797 THE CONTROVERSY GRIOWS .................. ................... 798 D'HERELLE IS DISCREDITED ...................................
Avian infectious bronchitis (IB), caused by a gammacoronavirus, is an OIE-listed (List B) disease and characterized by respiratory and renal involvements, causing high mortality, and economic loss in both layers and broilers. In comparison with other diagnostic methods, real-time polymerase chain reaction (RT-PCR) and conventional RT-PCR are potent, more sensitive and faster techniques for infe...
Corrigendum In the paper by Smith & Talbot (Br. J. Cancer 1992, 65, 787-793). Cisplatin and its analogues in the treatment of advanced breast cancer, additional data should be added to Table III.
Stroke is one of the major causes of death and disability worldwide. Approximately 85% of all strokes are ischemic, and 20% to 30% of these are caused by carotid atherosclerosis. Moderateto high-grade carotid artery stenosis can be detected in 1% to 3% of adults, and the incidence increases with age. Along with the degree of stenosis, inflammation and plaque composition are important in predict...
The high endemicity of hepatitis B virus (HBV) infection and liver disease in Sardinia led us to assess the occurrence of HBV DNA in 1,411 sera of two selected groups of hepatitis B surface antigen (HBsAg)-negative blood donors: 793 with abnormal serum alanine aminotransferase (ALT) and 618 with normal serum ALT values (determined during routine testing of their blood donation). HBV DNA sequenc...
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