Vulval carcinoma is becoming increasingly common. Thirty-four cases of vulval carcinoma were treated from 01/01/1992-31/12/2002. The mean age was 67, range (18-90). The presenting complaints were "a lump" (76%)(25/33), "itch" (49%)(16/33), "discomfort" (30%)(10/33) and postmenopausal bleeding (21%)(7/33). Most patients presented with stage 1 or 2 disease (73%) (n = 24/33). The majority (97%) (3...

BACKGROUND Responsiveness to GH treatment can be estimated by both growth and ∆IGF-I. The primary aim of the present study was to investigate if mimicking the physiological increase during puberty in GH secretion, by using a higher GH dose could lead to pubertal IGFs in short children with low GH secretion. The secondary aim was to explore the relationship between IGF-I, IGFBP-3 and the IGF-I/I...

accumulation, 71, 110, 111 non-ideal, 81 agarose, 33, 35, 44 pore size, 59 alkalinity, 35, 176, 183 aluminium, 44, 67, 176, 238 ammonia, 35, 176 ammonium persulphate, 33, 266 analytical techniques, 285 colorimetry, 181–182 computer imaging densitometry (CID), 181–182, 185, 202, 285 hyperspectral imaging, 182 laser ablation – ICPMS, 185–188, 285 PIXE, 175, 176 antimony, 44, 67, 135 area of windo...

We propose a human-in-the-loop approach for oracle improvement and analyse whether the proposed process is helping developers to create better oracles. For this, we conducted two human studies with 68 participants overall: an assessment study study. Our results show that exhibit poor performance (29 percent accuracy) when manually assessing assertion contains false positive, negative or none of...

Congenital adrenal hyperplasia (CAH) applies to a family of inherited disorders of steroidogenesis caused by an abnormality in one of the five enzymatic steps necessary in the conversion of cholesterol to cortisol. The enzyme defects are transmitted as an autosomal recessive trait. Patients with a "classical" form of CAH usually present during the neonatal and early infancy period with adrenal ...

6 1 Institut National de l’Environnement Industriel et des Risques (INERIS), Department of Experimental 7 Toxicology, Verneuil-en-Halatte, France 8 2 Université de Picardie Jules Verne (UPJV), Peritox Laboratoire de Périnatalité & Risques Toxiques UMR-I-01 9 Unité mixte INERIS, Amiens France 10 3 UPMC, Univ Paris 06, Centre MEG-EEG, Centre de Recherche de l'Institut du Cerveau et de la Moelle 1...

Four ruminally and duodenally cannulated beef steers (558 +/- 37 kg) were arranged in a 4 x 4 Latin square to evaluate the influence of crambe meal as a protein source on intake, digestion, and microbial efficiency. Steers were offered chopped (10.2 cm) brome hay (6.2% CP) for ad libitum consumption and one of four supplements. Protein sources used were soybean and crambe meals (CM). Protein so...

4 Service d’Endocrinologie et Maladies de la Reproduction, Assistance Publique-Hôpitaux de Paris, 14 Hôpital de Bicêtre, Le Kremlin-Bicêtre, F-94275, France. 15 16 Corresponding author’s address: Marc Lombès, INSERM U693, Faculté de Médecine Paris-Sud 11, 17 63, rue Gabriel Péri, 94276 Le Kremlin-Bicêtre Cedex France. E-mail: marc.lombes@u-psud.fr. Tel : 18 +33 1 49 59 67 09. Fax : + 33 1 49 59...