Female hypocretin knockout (Hcrt KO) mice have increased body weight despite decreased food intake compared to wild type (WT) mice. In order to understand the nature of the increased body weight, we carried out a detailed study of Hcrt KO and WT, male, and female mice. Female KO mice showed consistently higher body weight than WT mice, from 4 to 20 months (20-60%). Fat, muscle, and free fluid l...

The objective : to study the changes in lung microbiota inbred C57BL/6 mice after aerogenic infection with M. tuberculosis an experimental model. Subjects and Methods . This was carried out on 20 female of line weighing 20-22 grams which were infected a Glas-Col aerosol chamber (USA) culture virulent strain H37Rv at dose 400 CFU/lung. Morphological microbiological assessment lungs state perform...

Article history: Received: 11 Apr 2012 Accepted: 21 Aug 2012 Available online: 5 Jan 2013 ZJRMS 2014; 16(3): 64-66 Background: Pomegranate juice has several antioxidant components such as flavenoids and mineral materials such as sodium and potassium. In this study the effects of pomegranate juice on bone calcium content and body weight of adult mice were survived. Materials and Methods: In this...

bassia latifolia bud and cajanus cajan seed were evaluated for anti-fertility activity in mature female mice. anti-fertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. bassia latifolia bud and cajanus cajan seed extract arrested normal oestrous cycle at dioestrous stage. the decrease in weight of ovary and ute...

Bassia latifolia bud and Cajanus cajan seed were evaluated for anti-fertility activity in mature female mice. Anti-fertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. Bassia latifolia bud and Cajanus cajan seed extract arrested normal oestrous cycle at dioestrous stage. The decrease in weight of ovar...

The aim of the present study was to investigate the mechanisms underlying the desensitization of 5-HT(1A) receptors in the dorsal raphe and hypothalamus of serotonin (5-HT) transporter knock-out mice (5-HTT -/-). The density of 5-HT(1A) receptors in the dorsal raphe was reduced in both male and female 5-HTT -/- mice. This reduction was more extensive in female than in male 5-HTT -/- mice. 8-OH-...

The mouse system provides an excellent model for studying host resistance to Naegleria fowleri, the agent of primary amoebic meningoencephalitis. Innate resistance to infection with N. fowleri was examined with respect to infecting dose and the age, sex, and strain of mice. Intravenous inoculation with 10(7) amoebae per mouse produced 100% mortality in 9 days, whereas inoculation with fewer amo...