The title compound, C25H25N3O, comprises a 2-amino-pyridine ring fused with a cyclo-heptane ring, which adopts a chair conformation. The central pyridine ring (r.m.s. deviation = 0.013 Å) carries three substituents, viz. a benzyl-amino group, a meth-oxy-phenyl ring and a carbo-nitrile group. The N atom of the carbo-nitrile group is significantly displaced [by 0.2247 (1) Å] from the plane of the...

Objective(s):Involvement of tyrosinase in the synthesis of melanin and cell signaling pathway has made it an attractive target in the search for therapeutic inhibitors for treatment of different skin hyperpigmentation disorders and melanoma cancers. Materials and Methods: In the present study, we conducted a comprehensive kinetic analysis to understand the mechanisms of inhibition imposed by 2-...

In the mol-ecule of the title compound, [CdCl(2)(C(24)H(20)N(2))(2)], the Cd(II) centre has a distorted tetra-hedral coordination geometry defined by two chloride ions and two pyridine N atoms of the monodentate 2-[(triphenyl-meth-yl)amino]pyridine ligands. Weak intra-molecular N-H⋯Cl hydrogen bonds help to establish the three-dimensional architecture.

a thin-layer chromatography method has been developed and evaluated for the separation and determination of lysine and methonine in a mixture of amino acids obtained from acid or enzyme hydrolysis of protein. the solvent systems were (a) ethanol-ether, (b) phenol-water, (c) ethyl methyl ketone-pyridine-distilled water-glacial acetic acid. procedures in all the three stages were in the same dime...

The title compound, C(19)H(19)N(3)O(4)S(2), was prepared by the reaction of 2,3-diamino-pyridine with tosyl chloride in a mixture of dichloro-methane-pyridine as solvent. In the crystal, mol-ecules associate via pairs of N-H⋯N hydrogen bonds, forming a centrosymmetric eight-membered {⋯HNCN}(2) synthon. The dihedral angles between the amino-pyridine ring and the tosyl benzene rings are 50.01 (6)...

In the title solvated molecular salt, C(6)H(9)N(2) (+)·C(7)H(4)NO(4) (-)·CH(4)O, the pyridine N atom of 2-amino-4-methyl-pyridine is protonated and one carboxyl group of pyridine-2,6-dicarb-oxy-lic acid is deprotonated. The dihedral angles between the -CO(2) and -COH groups and the pyridine ring are 0.65 (13) and 7.4°. The crystal packing is stabilized by inter-molecular N-H⋯O, O-H⋯O and weak C...

Abstract The Pt(II) acetylacetonate complex [(L)Pt(Acac)] based on aminophenyl-substituted 2-(2-thienyl)pyridine (L) was synthesized, its photophysical properties were studied and compared with these for a similar containing no amino group in the ligand. structure of confirmed by X-ray diffraction (CIF file CCDC no. 2144689), 1 H 13 C NMR spectroscopy, ESI mass spectrometry, elemental analysis.

The crystal structures of N'-amino-pyridine-2-carboximidamide (C6H8N4), 1, and N'-{[1-(pyridin-2-yl)ethyl-idene]amino}-pyridine-2-carboximidamide (C13H13N5), 2, are described. The non-H atoms in compound 1 are nearly planar (r.m.s. deviation from planarity = 0.0108 Å), while 2 is twisted about the central N-N bond by 17.8 (2)°. Both mol-ecules are linked by inter-molecular N-H⋯N hydrogen-bondin...

Isolation and structure analysis of two amino acids from bovine ligamentum nuchae elastin hydrolysates revealed the presence of pyridine cross-links in elastin. The structures of these amino acids were determined to have 3,4,5- and 2,3,5-trisubstituted pyridine skeletons both with three carboxylic acids and a mass of 396 (C(18)H(28)N(4)0(6)) identified as 4-(4-amino-4-carboxybutyl)-3,5-di-(3-am...