Herein we report the clinical, histopathological, and molecular features of a cancer syndrome with predisposition to uterine leiomyomas and papillary renal cell carcinoma. The studied kindred included 11 family members with uterine leiomyomas and two with uterine leiomyosarcoma. Seven individuals had a history of cutaneous nodules, two of which were confirmed to be cutaneous leiomyomatosis. The...

To evaluate the frequency and appropriateness of indwelling urinary catheters (IUC) use and the incidence of catheter-associated urinary tract infections (CA-UTI), and explore the risk factors for CA-UTI in hospitals as a whole, we conducted a study. This study was divided into two parts; a point-prevalence study on Dec 12th 2012 and a prospective cohort study from Dec 13th 2012 to Jan 9th 2013...

The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily. Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen. Genetic linkage studies by re...

The second-order magneto-optical effects, represented by Voigt and Sch\"afer-Hubert are effective methods to detect the spin textures in antiferromagnets, whereas previous studies usually limited collinear antiferromagnets. In noncollinear characterized chirality have been revealed play a critical role many exciting physics. particular, first-order topological effects originated from scalar dis...

A proportion of gastrinomas demonstrates aggressive growth, and most deaths occur in this group. Little is known about the molecular pathogenesis of growth of this tumor, and there are no predictive factors that are useful in an individual patient. Chromosome 1 (Chr 1) loss of heterozygosity (LOH) is frequent in a number of nonendocrine tumors and in a few endocrine tumors, and its presence can...

Given a compact, connected Lie group K, we use principal K-bundles to construct manifolds with prescribed finite-dimensional algebraic models. Conversely, let M be a compact, connected, smooth manifold which supports an almost free K-action. Under a partial formality assumption on the orbit space and a regularity assumption on the characteristic classes of the action, we describe an algebraic m...

More than 550 breast adenocarcinomas with clonal chromosomal abnormalities have been reported. Although the aberration pattern is clearly nonrandom, no specific primary or secondary karyotypic abnormality has been identified, and furthermore the chronological order in which the aberrations appear during disease progression is not well known. The high degree of karyotypic complexity in epithelia...

Abstract Ependymoma (EPN) posterior fossa group A (PFA) has the highest rate of recurrence and worst prognosis all EPN types. At relapse, it is typically incurable even with re-resection re-irradiation. The biology recurrent PFA remains largely unknown, which hinders clinical advances. In this longitudinal large multicenter study, we examined matched samples primary disease from patients (n=95)...