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Inhibition of the bile salt export pump (BSEP) can cause intracellular accumulation of bile acids and is a risk factor for drug-induced liver injury in humans. Antiretroviral protease inhibitors lopinavir (LPV) and ritonavir (RTV) are reported BSEP inhibitors. However, the consequences of LPV and RTV, alone and combined (LPV/r), on hepatocyte viability, bile acid transport, and endogenous bile ...
Rhenium-188 Production in Hospitals, by W-188/Re-188 Generator, for Easy Use in Radionuclide Therapy
تهیه ترکیب فسفرتری کلرید بااستفاده از واکنش فسفر سفید(زرد) و گاز کلر در فاز محلول و درمقیاس آزمایشگاهی موردمطالعه قرارگرفت .پس از انتخاب مناسبتر روش و انتخاب بهترین شرایط کوشش درجهت طراحی واحد نیمه صنعتی انجام شد و توانستیم دراین راستا به تولید 10 کیلوگرم درساعت باخلوص 99/5 درصد برسیم . abstract the preparation of phosphorous trichloride by the reaction of white phosphorous and chlorine gas in ...
Functional programming is among paradigms used for the real-world parallel application development. PSI of RAS during a considerable period of time develops the T-System approach based on functional programming. This paper briefly describes the architecture of the ACCT compiler system targeted at performing transformations of the TSystem programs. An algorithm for nonlocal optimizing transforma...
Introduction: Previously, 186Re and 188Re radioisotopes have been produced through appropriate activities, and each of them has been used for therapeutic applications. The 186Re and 188Re have unique properties, which make them proper for the treatment of tumors in different sizes. The long-range 188Re, is suitabl...
The influence of genotypes for kappa-casein gene on the main indicators milk productivity in 1st and 3rd lactation black-and-white Kholmogory cows was studied. genotyping CSN3 carried out by method DNA diagnostics. Cows breed with genotype BB surpass group AA AB yield 166-218 fat 4.9-8.7 kg; 188-298 kg 7.7-10.2 kg, respectively. At same time difference is significant terms mass fraction protein...
Oxaliplatin (OXP) was reported to show low anti-tumor activity when used alone and to display side effects; this low activity was attributed to high partitioning to erythrocytes and low accumulation in tumors. Thermosensitive liposomes (TSL) were considered able to specifically deliver drugs to heated tumors and to resolve the OXP distribution problem. Regretfully, TSL encapsulating doxorubicin...
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