The propolis used in this study is from Brunei Darussalam, including G. thoracica, H. itama, and T. binghami. This focuses on evaluating phytochemicals, the total content of polyphenols flavonoids, marker compounds, anti-fungal activity Brunei. Until now, research compounds contained still being carried out. However, literature chemical compound limited. results using LC-MS/MS found as many 21 ...

Glycyrrhetinic acid (Ia) and fourteen derivatives of glycyrrhetinic acid were examined to estimate the antinociceptive activity (tests on writhing and vascular permeability induced by 0.7% acetic acid) and anti-type IV allergic effects in mice. Among them, three dihemiphthalate compounds (IIf, IIIc, IVc) derived from, deoxoglycyrrhetol (IIa), showed strong inhibition of writhing and dye leakage...

Background and Objectives: Medicinal pastilles are soft candies made (solidified) of thick liquids containing medicinal active ingredients. Licorice and its extracts are within the most important herbal plants used in various food industries and confectionaries. The substance is effective against diseases such as bronchitis and gastric ulcers. Materials and Methods: In this study, effects of a...

BACKGROUND Compatibility of Radix Aconiti Carmichaeli and Liquorice is known to treat heart diseases such as heart failure and cardiac arrhythmias. This work answers the question that whether the active components (Aconitine, Liquiritin and Glycyrrhetinic Acid) of Radix Aconiti Carmichaeli and Liquorice could result in regulating intracellular calcium homeostasis and calcium cycling, and thereb...

The triblock 18β-glycyrrhetinic acid-poly(ethylene glycol)18β-glycyrrhetinic acid conjugates (GA-PEG-GA) based self-assembled micelles were synthesized and characterized by FTIR, NMR, transmission electron microscopy, and particle size analysis. The GA-PEG-GA conjugates having the critical micelle concentration of 6 × 10(-5) M were used to form nanosized micelles, with mean diameters of 159.21 ...

Tumor cells expressing the herpes simplex virus type 1 thymidine kinase (HSV-tk) gene are killed by nucleoside analogues such as ganciclovir (GCV). GCV affects not only the cells expressing HSV-tk but also neighboring cells that do not express the gene; this phenomenon commonly is called "bystander effect." GCV metabolites transfer via gap junctional intercellular communication (GJIC) accounts ...

background herpes simplex virus 1 (hsv-1) resistance to drugs and the side effects of drugs have drawn the attention of investigators to herbal plants. objectives the main aim of the current research was to investigate the effects of glycyrrhiza glabra (liquorice root) on hsv-1. one of the objectives of the current research was to determine the efficacy and the effect of the elapsed incubation ...