Purpose: Intracellular calcium (Ca2+) signaling plays a role in many cellular events, such as cell proliferation and differentiation, gene transcription, oxidative stress, the antioxidant system, apoptosis. Transient receptor potential vanilloid 4 (TRPV4) channels are non-selective cation channels. The present study aims to investigate cytotoxic activity of RN-1734, transient antagonist, G361 h...