To determine the susceptibility of developing brain and other tissues to accumulate zinc, rats were exposed to zinc at different periods of ontogeny. For the prenatal group, pregnant Wistar rats received 50 ppm of zinc (ZnSO4 · 7H2O) in drinking for the entire duration of pregnancy. On the day of delivery zinc was removed from the drinking water. Another group, dams, received 50 ppm of zinc in ...

The objective of this study was to (1) examine the relationship between nitrate (NO₃-N) levels in public water supplies and risk of death from childhood brain tumors (CBT) and (2) determine whether calcium (Ca) and magnesium (Mg) levels in drinking water might modify the effects of NO₃-N on development of CBT. A matched cancer case-control study was used to investigate the relationship between ...

The relationship of dietary protein to cadmium absorption and tissue deposition was studied in male Sprague-Dawley rats exposed to different levels of cadmium in the drinking water. In animals fed a high-protein or low-protein diet and drinking water containing 25 or 50 ppm cadmium, liver and kidney cadmium and metallothionein were both significantly higher in rats fed the high-protein diet for...

It has been shown that molecular hydrogen (H(2)) acts as a therapeutic antioxidant and suppresses brain injury by buffering the effects of oxidative stress. Chronic oxidative stress causes neurodegenerative diseases such as Parkinson's disease (PD). Here, we show that drinking H(2)-containing water significantly reduced the loss of dopaminergic neurons in PD model mice using both acute and chro...

Ground water pollution causes adverse damage to soil, plants, human and animals at the same time spreads serious diseases. Ground water pollution can also cause biochemical effects such as inhibition of enzymes, genetic damage, and hypertension etc due to higher concentration of trace metals in the ground water. The present investigation is directed towards analysis of major metal ion concentra...

A novel dinuclear copper chemosensor selectively binds cyanide over a wide range of inorganic anions, enabling it to detect cyanide in water up to 0.02 ppm which is 10 times lower than the EPA standard for drinking water.

Cattle drinking water is a source of on-farm Escherichia coli O157:H7 transmission. The antimicrobial activities of disinfectants to control E. coli O157:H7 in on-farm drinking water are frequently neutralized by the presence of rumen content and manure that generally contaminate the drinking water. Different chemical treatments, including lactic acid, acidic calcium sulfate, chlorine, chlorine...

The main source for Campylobacter spp. transmission from the environment to broiler chickens is still unclear. One implicated reservoir for the organism has been untreated broiler drinking water. This study was conducted with broilers first using experimental conditions (isolation units) and second under commercial conditions. We compared the rate of intestinal colonization in chickens provided...

Unleaded gasoline (UG), a nongenotoxic kidney carcinogen in male, but not female, F344 rats or either sex of mice, and 2,2,4-trimethylpentane (TMP), a representative nephrotoxic isoparaffinic component of UG, were tested for potential promoting and cocarcinogenic effects in a kidney initiation-promotion model. The promotion study was conducted with 305 male and 305 female F344 rats fed 170 ppm ...

Parotid ductal saliva fluoride concentrations were determined as an indication of baseline plasma fluoride levels in three groups of children. Group I had been exposed to drinking water containing less than 0.1 ppm F and had not received fluoride supplements. Group II had consumed optimally fluoridated water (1 ppm) since infancy. Group III had consumed water with less than 0.1 ppm F but had re...