Kim P. Wagenaar, Berna D. L. Broekhuizen, Kenneth Dickstein, Tiny Jaarsma, Arno W. Hoes and Frans H. Rutten, Effectiveness of an interactive platform, and the ESC/HFA website in patients with heart failure: design of the multicentre randomized e-Vita heart failure trial, 2015, European Journal of Heart Failure, (17), 12, 1310-1316. http://dx.doi.org/10.1002/ejhf.413 Copyright: Oxford University...

The geography of innovation traditionally concentrates on localised knowledge spillovers, yet neglects collaboration networks as a means to access knowledge outside the region. Using publication and patent data for 1316 regions in the EU27 plus Norway and Switzerland, we find that both localised knowledge spillovers and the knowledge spillovers stemming from collaboration affect the innovative ...

El artículo tiene por objetivo analizar los aspectos punitivos y disciplinares de las constituciones la provincia Toscana producidas entre 1292 1316 en Orden Frailes Menores, así como determinar si conflictos que atravesaba orden aquellos tiempos impactaron o no nuevas legislaciones. Por otro lado, estudiaremos el aspecto regulatorio integral: cuándo existe una falta pasible ser punida, qué...

Abstract Background Epidural hematoma constitutes a common condition in neuro-traumatology. If its acute form is well known, the chronic one remains less described. In this study, we aimed to evaluate epidemiology, presentations, management, and outcomes of epidural (CEDH). Method Systematic searches PubMed, Google Scholar, ScienceDirect were performed from database searching for all studies re...

Insulin stimulates the autophosphorylation of the partially purified insulin receptor initially on tyrosine residues 1146, 1150 and 1151. This is followed by increased autophosphorylation of tyrosine residues 1316, 1322 and two further residues, possibly tyrosine residues 953 and 960 or 972 [Tavaré & Denton (1988) Biochem. J. 252, 607-615]. In the present paper we have used two cell lines trans...

Human birth weight is subject to stabilizing selection; babies born too small or too large are less likely to survive. Particular combinations of maternal/fetal immune system genes are associated with pregnancies where the babies are ≤ 5th birth weight centile, specifically an inhibitory maternal KIR AA genotype with a paternally derived fetal HLA-C2 ligand. We have now analyzed maternal KIR an...