PURPOSE Properties of potassium outward currents were investigated in human hippocampal dentate gyrus granule cells from 11 hippocampal specimens obtained from patients with temporal lobe epilepsy (TLE) during resective surgery. METHODS Dentate granule cells were isolated enzymatically and outward currents analyzed by using the whole-cell configuration of the patch-clamp method. Hippocampal s...

OBJECTIVE We wanted to determine whether combined radiofrequency ablation (RFA) and acetic acid-hypertonic saline solution (AHS) instillation can increase the extent of thermally mediated coagulation in in vivo rabbit liver tissue. We also wished to determine the optimal concentration of the solution in order to maximize its effect on extent of the RFA-induced coagulation. MATERIALS AND METHO...

Valproic acid (VPA) is a widely used antiepileptic drug to treat epilepsy and psychiatric disorders, but potentially causes idiosyncratic liver injury. Alpers-Huttenlocher syndrome (AHS), a neurogenetic disorder caused by mitochondrial DNA polymerase γ (POLG) mutations, has close correlation with fatal VPA hepatotoxicity. However, the mechanisms of this clinical mystery remain unknown. Here, we...

End users of Adaptive Hypermedia Systems (AHS) receive an experience that has been tailored towards their specific needs. Several AHS have produced favourable results showing benefits to the user experience [2]. However, the nature of AHS is that they tend to operate across a focused and fixed domain with a single body of content that is known a priori. This approach limits the user’s freedom t...

Emotion regulation involves the use of strategies to influence the experience and expression of emotions. Anxiety and depression are strongly associated with the positive symptoms of schizophrenia, such as auditory hallucinations (AHs). Individuals usually try to down-regulate (decrease) such emotions, consequently abnormal or maladaptive use of one or more of these down-regulatory processes (e...

BACKGROUND Factors associated with tobacco smoking are useful in designing tobacco control programs. OBJECTIVES To estimate the prevalence of and factors associated with tobacco smoking among long-distance drivers. METHODS This was a cross-sectional study. Stratified cluster sampling approach was used to select drivers based on if they received annual health screening (AHS) or not (non AHS)...

Central and Southern Africa are generally regarded as being endemic areas for African horse sickness (AHS). With the advent of the concepts of risk analysis and regionalisation/zoning, however, the possibility has now arisen of establishing 'zones' within South Africa for AHS surveillance purposes. In 1993, a protocol was submitted to the European Community (now European Union: EU), proposing t...

This study was conducted to determine the effect of dietary turmeric rhizome powder (TRP) as a natural antioxidant, and soybean oil, canola oil and tallow on lipid metabolism, blood metabolites, immune system, and antioxidant status of broiler chickens before (BHS, 28 d) and after exposure to heat stress (AHS, 42 d). Seven hundred and ninety two d-old male Arian broilers were randomly allotted ...

Increasing highway traffic congestion and real estate costs that limit the building of new highways has brought about a renewed interest in an Automated Highway System (AHS) where the vehicle steering task (“lateral control”) and the braking/throttle tasks (“longitudinal control”) are taken over by computers to increase the throughput of existing highways. Since safety plays a key role in the d...