the gallbladder remains a challenging clinical problem. Intraluminal brachytherapy (ILBT) and interstitial brachytherapy (IBT) have been found to be effective in improving local control in patients with the advanced unresectable carcinoma. Our previous research demonstrated that the combination of radioactive stents and normal metallic or plastic stents was technically feasible and well tolerat...

in this research, the effects of pulsing application of preservative solutions containing salicylic acid (100 and 200 mg/l) and methyl jasmonate (25 and 50 mg/l) and long period application of preservative solutions containing thymol (75 and 125 mg/l), menthol (75 and 125 mg/l) and eugenol (50 and 100 mg/l) on the maintain quality and extend vase-life of carnation cut flowers two tests were eva...

OBJECTIVES To test whether ciprofloxacin, moxifloxacin and clarithromycin affect the expression of the T helper (Th) cell cytokines, interferon-gamma and interleukin-4. Quinolone and macrolide antibiotics are routinely used for the treatment of critically ill patients with sepsis. These antibiotics modulate some aspects of immune cell function. Alteration in the profile of Th cell cytokine expr...

Objective To investigate the effect and mechanism of action of metformin on proliferation of a human hypopharyngeal carcinoma cell line (FaDu). Methods FaDu cells were treated with metformin (25-125 mmol/l). Cell proliferation was evaluated via CCK-8 assay. Real-time quantitative reverse transcription-polymerase chain reaction was used to evaluate microRNA (miR)-21-5p and PDCD4 (programmed cell...

1. Binding of l-tri-[(125)I]iodothyronine to the cytosol fraction of normal human female breast adipose tissue was investigated by the charcoal adsorption method. Equilibrium of binding was reached after 120s at 25 degrees C. 2. The l-tri-[(125)I]iodothyronine-binding component is a protein; this was confirmed by experiments in which binding was totally lost after heating the cytosol fraction f...

To the Editor: A 21-year-old woman presented with a history of abdominal pain, occasional vomiting, and fever of 2 weeks’ duration. She had no respiratory symptoms, and her past history was unremarkable. On examination she had a low-grade fever and mild tenderness in the abdomen. No masses were felt in the pelvis. Her white cell count was 3.7×10/l, and blood culture was negative. The chest radi...

BACKGROUND Recent insights provide support for the treatment of cancer during pregnancy, a coincidence that poses both mother and fetus at risk. Our aim was to critically review studies on the physiologic variations during pregnancy, the most common tumor markers used in diagnosis and follow-up of gynecological cancers. METHODS We conducted a systematic review of six tumor markers during norm...

Amylin (islet amyloid polypeptide) is the chief component of the islet amyloid found in type 2 diabetes, and amylin fibril precursors may be cytotoxic to pancreatic beta-cells. Little is known about the prevention of amylin aggregation. We investigated the role of insulin-degrading enzyme (IDE) in amylin degradation, amyloid deposition, and cytotoxicity in RIN-m5F insulinoma cells. Human (125)I...

We performed a parallel evaluation of 5 automated reticulocyte analyzers. The guidelines were those proposed by the National Committee for Clinical Laboratory Standards and the International Council for Standardisation in Haematology. Duplicate analyses were performed for 225 healthy subjects and 115 patients affected by various diseases. The reference intervals were different for each method (...