AM-112 [(1'R,5R,6R)-3-(4-amino-1,1-dimethyl-butyl)-6-(1'-hydroxyethyl)oxapenem-3-carboxylate] is a novel oxapenem compound which possesses potent beta-lactamase-inhibitory properties. Fifty-percent inhibitory concentrations (IC(50)s) of AM-112 for class A enzymes were between 0.16 and 2.24 micro M for three enzymes, compared to IC(50)s of 0.008 to 0.12 micro M for clavulanic acid. Against class...

This paper describes the three main improvements made to the solver Abscon 109 [9]. The new version, Abscon 112, is able to automatically break some variable symmetries, infer allDifferent constraints from cliques of variables that are pair-wise irreflexive, and use an optimized version of the STR (Simple Tabular Reduction) technique initially introduced by J. Ullmann for table constraints. 1 F...

Significant differences in the relationships between fragment, neutron, and charged particle multiplicities were found between Sn+Sn and Sn+Sn collisions at 40 MeV/A. In this paper we explore the possibility to explain this phenomenon in the framework of percolation models, and find, that the results are only reproducible in part.

Percolation models have proven highly successful in the simulation of multifragmentation reactions in the past @1,2#. Within these models, fragmentation is described by first distributing a set of points or sites, each representing a nucleon, on a three-dimensional lattice, which represents the bonds between the sites. In the case of a simple rectangular lattice, each site is connected to six n...

The heart is the first organ to form and to function during vertebrate embryogenesis and its correct functionality is a “conditio sine qua non” for life. If the heart’s pumping power is compromised, chambers dilate and pulmonary and systemic circulations are altered. Dilated cardiomyopathy can appear along a wide spectrum of presentations, including no symptoms, subtle symptoms or heart failure...

Carriers of bovine anaplasmosis in Northern Kerala, South India were detected using conventional microscopical and molecular techniques. PCR-RFLP and nested PCR techniques were used for detection of Anaplasma marginale and Anaplasma bovis respectively and the PCR products were confirmed by sequencing. Out of 150 samples tested, 25 were detected positive for A. marginale and five for A. bovis ba...

A new one-dimensional clarifier model was developed, including components of existing models, and extended with a height-dependent cross-sectional area and two flowrate-dependent dispersion coefficients. This model is evaluated using data from a detailed one-month measuring campaign on a full-scale wastewater treatment plant. The data included hourly sludge concentration profiles, sludge bed he...