We have studied the interrelations of myocardial oxygen metabolism and myocardial blood flow in hemorrhagic shock. Myocardial blood flow was measured by the Xe-washout method in closed-chest anesthetized dogs while the dogs were breathing either room air at ambient pressure or oxygen at high pressure. In animals with normal blood pressure, oxygen at high pressure produced a consistent decrease ...

The aims of surgical treatment for cholesteatoma include complete removal of disease and formation of a dry, self cleaning ear in addition to hearing reconstruction. This presentation concentrates on techniques of open mastoid surgery or modified radical mastoidectomy to achieve a well-constructed cavity. This study analyzes both primary and revision mastoid surgery referred to the author. ...

We have studied the interrelations of myocardial oxygen metabolism and myocardial blood flow in hemorrhagic shock. Myocardial blood flow was measured by the Xe-washout method in closed-chest anesthetized dogs while the dogs were breathing either room air at ambient pressure or oxygen at high pressure. In animals with normal blood pressure, oxygen at high pressure produced a consistent decrease ...

BACKGROUND AND PURPOSE Tracer studies have demonstrated that 100% oxygen inhalation causes a small cerebral blood flow (CBF) decrease. This study was performed to determine whether arterial spin-labeling (ASL), a noninvasive MR imaging technique, could image these changes with clinically reasonable imaging durations. MATERIALS AND METHODS Continuous ASL imaging was performed in 7 healthy subj...

The objective of the present study was to evaluate the antidepressant action of Withania somnifera (WS) as well as its interaction with the conventional antidepressant drugs and to delineate the possible mechanism of its antidepressant action using forced swimming model in mice. Effect of different doses of WS, fluoxetine and imipramine were studied on forced swimming test induced mean immobili...

S100 proteins were first discovered in 1965 by Moore as a major protein fraction (0.6% of total soluble protein) isolated from bovine brain (Moore 1965). The protein was given the name S100 due to its high solubility in saturated ammonium sulfate. Later experiments showed the S100 protein fraction constituted two different dimeric species comprised of two b protomers (S100B) or an a, b heterodi...

Isometric contractions induced by neuromuscular electrostimulation (NMES) have been shown to result in a prolonged force decrease but the time course of the potential central and peripheral factors have never been investigated. This study examined the specific time course of central and peripheral factors after isometric NMES-induced muscle damage. Twenty-five young healthy men were subjected t...

S100P protein consists of 95 amino acids with a molecular weight of 10.4 kDa. S100P is a Ca binding protein that belongs to S100 family ("Soluble in 100% saturated solution with ammonium sulfate") which was first isolated from human placenta and is therefore designated as "P". S100 family includes at least 26 members, which are thought to be expressed only in vertebrates and are present in a ti...