Transforming growth factor-β (TGF-β) is central during the pathogenesis of pulmonary fibrosis, in which the plasminogen activator inhibitor-1 (PAI-1) also has an established role. TGF-β is also known to be the strongest inducer of PAI-1. To investigate the link between PAI-1 and TGF-β in fibrotic processes, we evaluated the effect of SK-216, a PAI-1-specific inhibitor, in TGF-β-dependent epithe...

E. R # Sp Data Growth over the Years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 Taxonomy Analysis, Most Sequenced Phyla and Genera . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212 Basic Genome Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 Thousands of Genome Sequences . . . . . . . . . . . . . ....

This short note is an erratum to the article [R. Joubaud and G. Stoltz, Nonequilibrium shear viscosity computations with Langevin dynamics, Multiscale Model. Sim., 10 (2012), pp. 191–216]. We present required modifications in the proofs of Theorem 2 and 3.

The mortality of burn patients remains high in spite of the advances made in treating initial burn shock, controlling burn wound infection, and providing nutritional support. Smoke inhalation is recognized as a strong determinant of morbidity and mortality in burn patients, and most burn patients die because of associated inhalation injury. There are many reports on this combined injury (cutane...

The large main-belt asteroid (216) Kleopatra has been for long suspected to be a binary object, mainly due to its large lightcurve amplitude. However, recent observations suggest that it is a single “bone-shaped” or bi-lobated body (Ostro et al. 2000; Tanga et al. 2001). We present results obtained from ground-based adaptive optics observations, and in agreement with the radar raw-observations,...

Candidemia was simulated with 15 Candida spp. by using an automated blood culture system. Candida growth was detected in 479/648 (74%) bottles: 211/216 (98%) aerobic bottles, 58/216 (27%) anaerobic bottles, and 210/216 (97%) mycology bottles. Only the growth of Candida lipolytica failed to be detected in all media.

We report here identification of novel mimicry epitopes for interphotoreceptor retinoid-binding protein (IRBP) 201-216, a candidate ocular antigen that causes experimental autoimmune uveoretinitis (EAU) in A/J mice. One mimicry epitope from Ehrlichia canis (EHC), designated EHC 44-59, induced cross-reactive T cells for IRBP 201-216 capable of producing T helper (Th)1 and Th17 cytokines, but fai...