This is the first part of a two week experiment in image processing. During this week, we will cover the fundamentals of digital monochrome images, intensity histograms, pointwise transformations, gamma correction, and image enhancement based on filtering. In the second week , we will cover some fundamental concepts of color images. This will include a brief description on how humans perceive c...

OBJECTIVE To determine the optimal methotrexate dose in individual patients and to explore whether this optimal dose and the level of disease activity at that dose could be predicted. METHODS Data from CAMERA II trial comparing MTX and MTX with 10 mg of prednisone both in a tight control treatment strategy in early RA was used. For each patient a curve for disease activity over time was fitte...

Open Access Week, starting 24 October 2016, is a worldwide event established to promote the potential benefits of open access and to foster wider participation in helping to make open access the norm in research and information sharing. In its eighth year, Open Access Week presents an opportunity for funding bodies, universities and others to use the context to advance policy changes in favour ...