Angiotensin II (Ang II) up-regulates plasminogen-activator inhibitor type-1 (PAI-1) expression in mesangial cells to enhance extracellular matrix formation. The proximal promoter region (bp -87 to -45) of the human PAI-1 gene contains several potent binding sites for transcription factors [two phorbol-ester-response-element (TRE)-like sequences; D-box (-82 to -76) and P-box (-61 to 54), and one...

Fractals can model many classes of time-seri" data. The fractal dimension is an important actertsfic of ftaqo& that coniai, c information . out their geometrical structure at multiple Ntod re a b g ms i l d h ti BC m h d t c s, : s a ass of CJJ4 ent proac ox-coun n ( } et over 1 g c es, e.g., o , o estimate the fractal-dimension. Jr. this paper, the d rential box-counting (DBC) approach, origin...

Roitman's combinatorial principle $\Delta$ is equivalent to monotone normality of the nabla product, $\nabla (\omega +1)^\omega$. If $\{ X_n : n\in \omega\}$ a family metrizable spaces and $\nabla_n X_n$ monotonically normal, then hereditarily paracompact. Hence, if holds box product $\square +1)^\omega$ Large fragments hold in $\mathsf{ZFC}$, yielding large subspaces (\omega+1)^\omega$ that ar...

In this paper we consider the relationship between the Assouad and box-counting dimension and how both behave under the operation of taking products. We introduce the notion of ‘equi-homogeneity’ of a set, which requires a uniformity in the size of local covers at all lengths and at all points We prove that the Assouad and box-counting dimensions coincide for sets that have equal upper and lowe...

Roald M. Tiggelaar a,d,1, Fernando Benito-López b,1, Dorothee C. Hermes a, Helmut Rathgen c, Richard J.M. Egberink b, Frieder G. Mugele c, David N. Reinhoudt b, Albert van den Berg a, Willem Verboom b, Han J.G.E. Gardeniers a,d,∗ a BIOS, Lab-on-a-Chip Group, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede, The Netherlands b Supramolecular Chemistry and ...

K e y w o r d s: Box-Cox transformation, SV model, Bayesian inference.

the anxiolytic effect of the flower of echium. amoenum was shown in several experimental studies in mice. the present study was aimed to determine whether tolerance develops to anxiolytic action of e. amoenum in mice. nmri male mice were injected intraperitoneal with hydroalcoholic extract (12.5, 25 and 50 mg/kg) or saline once each day (8 am) for period of 7 days and then tested on light/dark ...

Given a set of n points, P, in E d (the plane when d = 2) that lie inside a d-box (rectangle when d = 2) R, we study the problem of partitioning R into d-boxes by introducing a set of orthogonal hyperplane segments (line segments when d = 2) whose total (d?1)-volume (length when d = 2) is the least possible. In a valid d-box partition, each point in P must be included in at least one partitioni...