نتایج جستجو برای: 0402

تعداد نتایج: 153  

Journal: :Diabetes 2008
Henry Erlich Ana Maria Valdes Janelle Noble Joyce A Carlson Mike Varney Pat Concannon Josyf C Mychaleckyj John A Todd Persia Bonella Anna Lisa Fear Eva Lavant Anthony Louey Priscilla Moonsamy

OBJECTIVE The Type 1 Diabetes Genetics Consortium has collected type 1 diabetic families worldwide for genetic analysis. The major genetic determinants of type 1 diabetes are alleles at the HLA-DRB1 and DQB1 loci, with both susceptible and protective DR-DQ haplotypes present in all human populations. The aim of this study is to estimate the risk conferred by specific DR-DQ haplotypes and genoty...

2016
Nirag Kadakia Daniel Breen Uriel Morone Daniel Margoliash Henry D.I. Abarbanel

With the goal of building a model of the HVC nucleus in the avian song system, we discuss in detail a model of HVCRA projection neurons comprised of a somatic compartment with fast Na and K currents and a dendritic compartment with slower Ca dynamics. We show this model qualitatively exhibits many observed electrophysiological behaviors. We then show in numerical procedures how one can design a...

2002

Information ColumnsPack sizeCode No. HiTrap rProtein A FF5 × 1 ml17-5079-01 HiTrap rProtein A FF2 × 1 ml17-5079-02 HiTrap rProtein A FF1 × 5 ml17-5080-01 HiTrap Protein A HP5 × 1 ml17-0402-01 HiTrap Protein A HP2 × 1 ml17-0402-03 HiTrap Protein A HP1 × 5 ml17-0403-01 HiTrap Protein G HP5 × 1 ml17-0404-01 HiTrap Protein G HP2 × 1 ml17-0404-03 HiTrap Protein G HP1 × 5 ml17-0405-01 HiTrap Blue HP5...

Journal: :Journal of immunology 2001
A Snijders D G Elferink A Geluk A L van Der Zanden K Vos G M Schreuder F C Breedveld R R de Vries E H Zanelli

Predisposition to rheumatoid arthritis (RA) is thought to be associated with HLA-DR1, -DR4, and -DR10. However, many epidemiological observations are better explained by a model in which the DQ alleles that are linked to these DR alleles, i.e., DQ5, DQ7, and DQ8, predispose to RA, while certain DR alleles have a dominant protective effect. All protective DRB1 alleles, e.g., *0402, *1301, and *1...

2016
Nirag Kadakia Eve Armstrong Daniel Breen Uriel Morone Arij Daou Daniel Margoliash Henry DI Abarbanel

With the goal of building a model of the HVC nucleus in the avian song system, we discuss in detail a model of HVCRA projection neurons comprised of a somatic compartment with fast Na and K currents and a dendritic compartment with slower Ca dynamics. We show this model qualitatively exhibits many observed electrophysiological behaviors. We then show in numerical procedures how one can design a...

2014
Victor Malievsky Tatyana Victorova Ksenia Danilko Liliia S Nazarova

Introduction Juvenile idiopathic arthritis (JIA) refers to a group of conditions involving joint inflammation that first appears before the age of 16. Juvenile idiopathic arthritis is thought to arise from a combination of genetic and environmental factors. Numerous associations between HLA polymorphisms and JIA subtypes have been reported in multiple populations. The HLA region SNP rs7775055 i...

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