The two general treatment approaches for esophageal cancer are primary treatment (surgical or nonsurgical) or adjuvant treatment (preoperative or postoperative). Due to differences in the patient populations selected for surgical or nonsurgical therapies, which may bias the results against nonsurgical therapy, it is difficult to determine the best treatment approach for this disease. The standa...

A search for millimetric continuum emission from eight optically-selected, radio-quiet quasars and a radiogalaxy with 3.7 < z < 4.3, has been undertaken using a highly sensitive 7-channel bolometer on the IRAM 30-m Millimetre Radio Telescope. Detections of a potentially dust-rich quasar, and of 8C1435+635, the most distant known radiogalaxy, are reported. An extrapolation of the steepening cent...

Serotypes and antibiotic resistance of 51 Verotoxigenic (VTEC) and 33 Necrotizing (NTEC) bovine Escherichia coli strains were determined and compared with those shown by 205 non-VTEC non-NTEC strains isolated from the same batch of calves. E. coli untypable for O-antigen represented 47% of the VTEC, 12% of the NTEC and 8.8% of the non-VTEC non-NTEC. Typable VTEC belonged to serotypes 02:K?, 010...

An ascent sequence is a sequence consisting of non-negative integers in which the size of each letter is restricted by the number of ascents preceding it in the sequence. Ascent sequences have recently been shown to be related to (2+2)-free posets and a variety of other combinatorial structures. In this paper, we prove some recent conjectures of Duncan and Steingŕımsson concerning pattern avoid...

PURPOSE Primary surgery followed by platinum/taxane-based chemotherapy is the standard therapy in advanced ovarian cancer. The prognostic role of complete debulking has been well described; however, the impact of systematic pelvic and para-aortic lymphadenectomy and its interaction with biologic factors are still not fully defined. METHODS This was an exploratory analysis of three prospective...

Fourier spectral method can achieve exponential accuracy both on the approximation level and for solving partial differential equations if the solutions are analytic. For a linear partial differential equation with a discontinuous solution, Fourier spectral method produces poor pointwise accuracy without post-processing, but still maintains exponential accuracy for all moments against analytic ...

Aim: To assess the use of anterior segment optical coherence tomography (OCT) as an adjuvant diagnostic tool in primary acquired melanosis (PAM) by correlating clinical, histopathologic and anterior segment OCT findings. Methods: Twenty-four patients (24 eyes) with PAM of the conjunctiva, cornea or both were imaged with an anterior segment OCT device (RTVue, model-RT100; Optovue Inc., Fremont, ...

Abstract Background The prevention of COVID-19 in vulnerable populations is a global health priority. EVADE was phase 2/3 multicenter, double-blind, randomized, placebo-controlled trial adintrevimab, an extended–half-life monoclonal antibody, for post-exposure (PEP) and pre-exposure prophylaxis (PrEP) symptomatic COVID-19. Methods Eligible participants (vaccine-naïve, aged ≥12 years) were rando...

It is well known that subspaces of the Hardy space over the unit disk which are invariant under the backward shift occur as the image of an observability operator associated with a discrete-time linear system with stable state-dynamics, as well as the functional-model space for a Hilbert space contraction operator. We discuss two multivariable extensions of this structure, where the classical H...