Purpose ; Effects of topically applied 0.1% dernmethrsone on epithelirl and endothelial healing following alkali wound were examined. Mehtods ; 30 New Zealand white rabbits were divided in 3 groups. By using a 5.5 mm round filter paper, alkali wounds ( 1N NaOH, 60s ) were produced in one eye of each animal. Group A treated with 0.1% dexamethasone, 3 x/day for 3 weeks. Group B received 0.1% dexa...

PURPOSE Ceramics have a long history in fixed prosthodontics for achieving optimal esthetics and various materials have been used to improve ceramic core strength. However, there is a lack of information on how color is affected by fabrication procedure. The purpose of this study was to evaluate the effects of various dentin ceramic thicknesses and repeated firings on the color of zirconium oxi...

Purpose ; Effects of topically applied 0.1% dernmethrsone on epithelirl and endothelial healing following alkali wound were examined. Mehtods ; 30 New Zealand white rabbits were divided in 3 groups. By using a 5.5 mm round filter paper, alkali wounds ( 1N NaOH, 60s ) were produced in one eye of each animal. Group A treated with 0.1% dexamethasone, 3 x/day for 3 weeks. Group B received 0.1% dexa...

Purpose ; Effects of topically applied 0.1% dernmethrsone on epithelirl and endothelial healing following alkali wound were examined. Mehtods ; 30 New Zealand white rabbits were divided in 3 groups. By using a 5.5 mm round filter paper, alkali wounds ( 1N NaOH, 60s ) were produced in one eye of each animal. Group A treated with 0.1% dexamethasone, 3 x/day for 3 weeks. Group B received 0.1% dexa...

Spontaneously hypertensive rats (SHR) are hyperinsulinemic compared with their Wistar-Kyoto (WKY) controls. Since previous studies have demonstrated that vanadyl sulfate lowers insulin levels in nondiabetic rats, we used vanadyl to explore the relation between hyperinsulinemia and hypertension. In a prevention study, 5-week-old SHR and WKY rats were started on long-term vanadyl sulfate treatmen...

Interactions between pharmacologic NFB inhibitors (eg, Bay 11-7082, SN-50) and the checkpoint abrogator UCN-01 have been examined in human multiple myeloma (MM) cells. Exposure of U266 cells to Bay 11-7082 (Bay) in combination with UCN-01 resulted in the abrogation of NFB/DNA binding activity and the synergistic induction of apoptosis. Comparable synergism was observed in other MM cell lines an...

OBJECTIVE America On the Move (AOM) is a national weight gain prevention initiative that promotes small lifestyle changes by increasing walking by 2000 steps/day and reducing energy intake by about 100 kcal/day. The study's intent was to determine the impact of these small changes recommendations on steps/day and energy intake. METHODS In this cross-sectional study, food and fluid intake and ...

The detailed integrated renal, hormonal, and hemodynamic effects of acute (first dose) and established (4 days) inhibition of endopeptidase 24.11 by SCH 42495 (200 mg, every 12 hours) were documented in eight patients with essential hypertension in a double-blind, balanced random-order, crossover study. SCH 42495 suppressed plasma endopeptidase activity (> 90%, P < .001) for the duration of the...

We characterized the in vivo cardiovascular profile of SCH 58261, 7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2, 4-triazolo[1,5-c] pyrimidine, a selective A2A adenosine receptor antagonist, in conscious, freely moving rats by use of the telemetry system. In normotensive rats, SCH 58261, at 10 mg/kg i.p., significantly (P < .05) inhibited hypotension and tachycardia induced by the A...