Carotid stenosis is generally associated with high risks of stroke and vascular events. In asymptomatic and symptomatic patients, with or without revascularization, optimal managements of carotid artery stenosis require the use of medications or lifestyle modifications (stopping smoking and monitoring hypertension, hyperlipidemia, and diabetes) to control the processes associated with atheroma ...

OBJECTIVE A post hoc analysis evaluated the effects of levomilnacipran ER on individual symptoms and symptom domains in adults with major depressive disorder (MDD). METHODS Data were pooled from 5 Phase III trials comprising 2598 patients. Effects on depression symptoms were analyzed based on change from baseline in individual Montgomery-Åsberg Depression Rating Scale (MADRS) item scores. A1d...

Norihiro Muroyama,† Arisa Yoshimura,‡ Yoshiki Kubota,‡ Keiichi Miyasaka,† Tetsu Ohsuna,§,| Ryong Ryoo,⊥ Peter I. Ravikovitch,# Alexander V. Neimark,*,∇ Masaki Takata,O and Osamu Terasaki*,† Structural Chemistry, Arrhenius Laboratory, Stockholm UniVersity, SE-10691 Stockholm, Sweden, Department of Physical Science, Graduate School of Science, Osaka Prefecture UniVersity, 1-1 Gakuen-cho, Naka-ku,...

The treatment of early-stage Hodgkin lymphoma remains controversial with combined modality therapy and chemotherapy alone representing acceptable options. Observation studies show a progressive decline in the use of radiation secondary to late complications but also suggest a decrease in survival for non-irradiated patients. Early PET CT scans have been incorporated into strategies of response-...

Random forests are a scheme proposed by Leo Breiman in the 2000’s for building a predictor ensemble with a set of decision trees that grow in randomly selected subspaces of data. Despite growing interest and practical use, there has been little exploration of the statistical properties of random forests, and little is known about the mathematical forces driving the algorithm. In this paper, we ...

Masticatory efficiency in individuals with extensive tooth loss has been widely discussed. However, little is known about jaw movement smoothness during chewing and the effect of differences in food bolus location on movement smoothness and masticatory efficiency. The aim of this study was to determine whether experimental differences in food bolus location (anterior versus posterior) had an ef...

A transshipment problem with demands that exceed network capacity can be solved by sending ow in several waves. How can this be done in the minimum number, T , of waves, and at minimum cost, if costs are piece-wise linear convex functions of the ow? In this paper, we show that this problem can be solved using minfm; logT; log(m U) 1+log(m U) log(mU) g maximum ow computations and one minimum (co...

Several recent studies have demonstrated that people show large behavioural uniqueness. This has serious privacy implications as most individuals become increasingly re-identifiable in large datasets or can be tracked, while they are browsing the web, using only a couple of their attributes, called as their fingerprints. Often, the success of these attacks depends on explicit constraints on the...

Carotid stenosis is generally associated with high risks of stroke and vascular events. In asymptomatic and symptomatic patients, with or without revascularization, optimal managements of carotid artery stenosis require the use of medications or lifestyle modifications (stopping smoking and monitoring hypertension, hyperlipidemia, and diabetes) to control the processes associated with atheroma ...