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Neural tube defects (NTDs) are congenital malformations which arise from incomplete closure of the neural tube during early embryogenesis. The most common types found in humans are spina bifida and anencephaly. These can occur together in a single family and in some cases even in one person. About 70–80% of all human NTDs show complex or multifactorial inheritance patterns, indicating that both...
Long-term molecular adaptations in liver from high-producing dairy cows are virtually unknown. Liver from five Holstein cows was biopsied at -65, -30, -14, +1, +14, +28, and +49 days relative to parturition for transcript profiling using a microarray consisting of 7,872 annotated cattle cDNA inserts. More than 5,000 cDNA elements represented on the microarray were expressed in liver. From this ...
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