نتایج جستجو برای: ژن magi2

تعداد نتایج: 15852  

Journal: :Heart Rhythm 2023

Higher burden of PVC is associated with heart failure and cardiovascular events. Genetic background pathogenesis premature ventricular complex (PVC) remain uncertain despite recent advances in mechanisms arrhythmogenesis. To study the genetic higher comparison very low PVC. A total 1222 patients both 24-hour Holter electrocardiogram data genomic were enrolled. Patients daily (<0.1%) defined as ...

2009
Eric D. Marsh Jeffrey A. Golden

clinical overview The early epileptic encephalopathies are a group of conditions that all manifest with three major diagnostic criteria: medically refractory seizures, diffuse encephalopathy and a poor developmental outcome. These syndromes include early infantile epileptic encephalopathy (EEIE, also known as Otahara’s syndrome), severe myoclonic epilepsy of infancy (Dravet’s syndrome), infanti...

2012
Omid Kohannim Derrek P. Hibar Jason L. Stein Neda Jahanshad Xue Hua Priya Rajagopalan Arthur W. Toga Clifford R. Jack Michael W. Weiner Greig I. de Zubicaray Katie L. McMahon Narelle K. Hansell Nicholas G. Martin Margaret J. Wright Paul M. Thompson

We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer's Disease Neuroimaging Initiative (ADNI). Sparse groups of SNPs in individual genes were selected by LASSO, which identifies effic...

Journal: :Development 2004
Gavin J Wright Jonathan D Leslie Linda Ariza-McNaughton Julian Lewis

Delta proteins activate Notch through a binding reaction that depends on their extracellular domains; but the intracellular (C-terminal) domains of the Deltas also have significant functions. All classes of vertebrates possess a subset of Delta proteins with a conserved ATEV* motif at their C termini. These ATEV Deltas include Delta1 and Delta4 in mammals and DeltaD and DeltaC in the zebrafish....

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