Shigella spp. cause hundreds of millions intestinal infections each year. They target the mucosa human colon and are an important model intracellular bacterial pathogenesis. is a pathovar Escherichia coli that characterized by presence large invasion plasmid, pINV, which encodes characteristic type III secretion system icsA used for cytosol cell-to-cell spread, respectively. First, we review re...

bacillary dysentery, or shigellosis, is a disease of humans in which the colonic epithelium is invaded by bacteria and subjected to inflammatory destruction. the aim of this study was to develop a polymerase chain reaction(pcr) test for detection of virulent shigella spp.. for this purpose, the primers were designed to amplify a 526-bp internal region of the shigella spp. icsa gene, which encod...

distribution of the Listeria monocytogenes ActA protein is required and sufficient to direct actin-based motility. Mol. (1995). The unrelated surface proteins ActA of Listeria monocytogenes and IcsA of Shigella flexneri are sufficient to confer actin-based motility on Listeria innocua and Escherichia coli respectively. Identification of icsA, a plasmid locus of Shigella flexneri that governs ba...

Bruxism is the repetitive muscle-mandibular behavior characterized by clenching and/or grinding of teeth, which reflects presence one or more underlying conditions factors. The objective this descriptive study was to determine association between bruxism and stress self-perceived during pandemic, as well their frequency gender academic area. An interrogation scale PSS-14 were applied students f...

The two-component signal transduction system PhoP/PhoQ is an important regulator for stress responses and virulence in most Gram-negative bacteria, but characterization of PhoP/PhoQ in Shigella has not been thoroughly investigated. In the present study, we found that deletion of phoPQ (ΔphoPQ) from Shigella flexneri 2a 301 (Sf301) resulted in a significant decline (reduced by more than 15-fold)...

Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in Shigella flexneri An S. flexneri clsA mutant had no cardiolipin detected within its membrane, grew normally in vitro, and invaded cultured epithelial cells, but it failed to form plaques in epithelial cell monolayers, indicating t...

Abstract Arrhythmias are variations in the heartbeat rhythm that occur frequently a human's life. These arrhythmias can result potentially deadly consequences, putting one's life danger. As result, detection and classification of is an important issue cardiac diagnostics. Electrocardiogram one easiest ways to diagnose heart disease but complexities due noise present it. This research introduced...

The objectives of this study were to examine the involvement of D1 and D2 receptors within the nucleus accumbens (ACB) in mediating reinforcement. The intracranial self-administration (ICSA) of D1 and D2 agonists was used to determine whether activating D1 and/or D2 receptors within the ACB of Wistar rats is reinforcing. At concentrations of 0.25, 0.50, and 1.0 mM (25, 50, and 100 pmol/100 nl o...