This paper presents a system for computer-aided thinking. We propose the idea of reflecting the mental world indirectly into a metric space to support such human thinking activities as externalizing and forming new ideas. We use a method that maps text-objects into metric spaces for visualizing a user’s thought space structure. Text-objects imply fragments of a user’s idea, which have several k...

Excess Leu reduces the availability of Ile and Val in pigs likely by reducing absorption of the latter amino acids (AA). Twenty-four crossbred pigs were used to evaluate the effect of excess Leu alone or with surplus Ile and Val on the expression of cationic (b(0),(+)AT and CAT1) and neutral (B(0)AT1) AA transporters in the small intestine, liver, and skeletal muscle. Dietary treatments include...

BACKGROUND Bemisia tabaci MEAM1 (Middle East-Asia Minor 1) feeding alters antioxidative enzyme activity in some plant species. Infestation of B. tabaci nymphs decreases Myzus persicae performance on systemic, but not local leaves of tobacco plants. However, it is unclear if B. tabaci nymphs induced antioxidant activities contributing to the aphid resistance. METHODOLOGY/PRINCIPAL FINDINGS We ...

Candida albicans is the most frequently encountered fungal pathogen in humans, capable of causing mucocutaneous and systemic infections in immunocompromised individuals. C. albicans virulence is influenced by multiple factors. Importantly, iron acquisition and avoidance of the immune oxidative burst are two critical barriers for survival in the host. Prior studies using whole genome microarray ...

Title: Ketogenic Diets as an Adjuvant Therapy in Glioblastoma (The KEATING Trial): Study Protocol for a Randomised Pilot Study Authors: Kirsty Martin-McGill ([email protected]) Anthony Marson ([email protected]) Catrin Tudur Smith ([email protected]) Michael Jenkinson ([email protected]) Version: 2 Date: 18 Aug 2017 Author’s response to reviews: Dear Dr Lehana ...

The intestinal Ca(2+) transport protein CaT1 has recently been shown to have the biophysical characteristics of the Ca(2+)-release activated Ca(2+) channel that refills internal Ca(2+) stores following agonist-elicited release. This finding highlights a hitherto unrecognized link between epithelial Ca(2+) transport and Ca(2+) signalling.