We present a lifetime measurements of the 6s level of rubidium. We use a time-correlated singlephoton counting technique on two different samples of rubidium atoms. A vapor cell with variable rubidium density and a sample of atoms confined and cooled in a magneto-optical trap. The 5P1/2 level serves as the resonant intermediate step for the two step excitation to the 6s level. We detect the dec...

Numerous biomolecules recognize the 7-methylguanosine cap structure present at the 5' ends of eukaryotic mRNAs. Photo-crosslinking is a valuable technique to study these interactions. We report three anti-reverse cap analogs containing a photo-activable nucleoside, 6-thioguanosine ((6S)G), that enable the synthesis of capped RNAs with (6S)G positioned exclusively as the first transcribed nucleo...

We present a lifetime measurement of the 6s level of rubidium. We use a time-correlated single-photon counting technique on two different samples of rubidium atoms, a vapor cell with variable rubidium density, and a sample of atoms confined and cooled in a magneto-optical trap. The 5P1/2 level serves as the resonant intermediate step for the two-step excitation to the 6s level. We detect the de...

The distribution, clearance, and bioavailability of (2S,6S)-hydroxynorketamine has been studied in the Wistar rat. The plasma and brain tissue concentrations over time of (2S,6S)-hydroxynorketamine were determined after intravenous (20 mg/kg) and oral (20 mg/kg) administration of (2S,6S)-hydroxynorketamine (n = 3). After intravenous administration, the pharmacokinetic parameters were estimated ...

We present accurate ab initio non-perturbative calculations of the Breit correction to the parity non-conserving (PNC) amplitudes of the 6s−7s and 6s−5d3/2 transitions in Cs, 7s−8s and 7s−6d3/2 transitions in Fr, 6s − 5d3/2 transition in Ba , 7s − 6d3/2 transition in Ra , and 6p1/2 − 6p3/2 transition in Tl. The results for the 6s− 7s transition in Cs and 7s− 8s transition in Fr are in good agre...

When gaseous mercury is subjected to an electrical discharge, such as in a fluorescent light bulb, street lamp, or laboratory discharge tube, the collisions between the mercury atoms and the electrons are energetic enough to excite one of the 6s electrons to a higher energy state, while the remaining 79 electrons (including the other 6s electron) remain undisturbed. Depending upon which empty s...

The natural folate derivative, 5-methyltetrahydrofolate ([6S]-5-MTHF), could be an option for supplementation and fortification but its bioavailability remains unclear. This study compared the bioavailability of [6S]-5-MTHF with that of folic acid (FA) by measuring plasma folate responses after a single ingestion of equivalent doses of the two folate forms. In a double-blind, crossover study, 1...

The trans-4-hydroxynonenal (HNE)-derived exocyclic 1, N(2)-dG adduct with (6S,8R,11S) stereochemistry forms interstrand N(2)-dG-N(2)-dG cross-links in the 5'-CpG-3' DNA sequence context, but the corresponding adduct possessing (6R,8S,11R) stereochemistry does not. Both exist primarily as diastereomeric cyclic hemiacetals when placed into duplex DNA [Huang, H., Wang, H., Qi, N., Kozekova, A., Ri...

Abstiuct-Remote sensing from satellite or airborne platforms of land or sea surfaces in the visible and near infrared is strongly affected by the presence of the atmosphere along the path from Sun to Target (surface) to Sensor. This paper presents 6s (Second Simulation of the Satellite Signal in the Solar Spectrum), a computer code which can accurately simulate the above problems. The 6S code i...

PURPOSE To analyze the amounts and distributions of nonsulfated and sulfated keratan sulfate (KS) and chondroitin/dermatan sulfate (CS/DS) disaccharides in the interface wound of human postmortem LASIK corneas in comparison with normal control corneas. METHODS Corneal stromal tissue samples from central and paracentral hypocellular primitive stromal interface scars of human LASIK corneas and ...