BACKGROUND AND PURPOSE Hematoma volume is the most potent predictor of outcome in spontaneous intracerebral hemorrhage (ICH), and hematoma expansion after hospital presentation occurs in up to 40% of individuals. Among patients with lobar ICH, the apolipoprotein E (APOE) ε2 allele predicts larger hematoma volumes at presentation. We investigated whether the ε2 allele also identifies individuals...

BACKGROUND Schistosomiasis mansoni is a parasitic liver disease, which causes several metabolic disturbances. Here, we evaluate the influence of Apolipoprotein E (APOE) gene polymorphism, a known modulator of lipid metabolism, on plasma lipid levels in patients with hepatosplenic schistosomiasis. METHODOLOGY/PRINCIPAL FINDINGS Blood samples were used for APOE genotyping and to measure total c...

We consider Maxwell’s equations for an isomagnetic anisotropic, non-stationary and inhomogeneous medium in two dimensions. We discuss an inverse problem of determining the permittivity tensor   ε1 ε2 ε2 ε3   and the permeability μ in the constitutive relations from a finite number of lateral boundary measurements. Applying a Carleman estimate, we prove an estimate of the Lipschitz type for ...

BACKGROUND Recent work has demonstrated the potentially protective effects of the apolipoprotein E (APOE) ε2 allele on cognitive functioning in individuals at risk for developing Alzheimer disease. However, little is known regarding the effect of ε2 genotype on rate of change in daily functioning over time. The aim of the current study was to examine the relationship between APOE genotype and c...

BACKGROUND AND PURPOSE The basis for decreased vulnerability to AD among apoE ε2 carriers is unknown. The purpose of this study was to use diffusion tensor imaging to detect possible differences in white matter integrity between cognitively normal elderly apoE ε2 carriers and apoE ε3/ε3 controls. MATERIALS AND METHODS Thirty-nine cognitively normal elderly individuals (19 heterozygous carrier...

We introduce and study a generalization of the well-known region of influence proximity drawings, called (ε1, ε2)-proximity drawings. Intuitively, given a definition of proximity and two real numbers ε1 ≥ 0 and ε2 ≥ 0, an (ε1, ε2)-proximity drawing of a graph is a planar straight-line drawing Γ such that: (i) for every pair of adjacent vertices u, v, their proximity region “shrunk” by the multi...