نتایج جستجو برای: واژگان کلیدی1 igf
تعداد نتایج: 34716 فیلتر نتایج به سال:
Abstract Acromegaly is a rare, chronic disease that is, in more than 95% of cases, caused by growth hormone (GH)-secreting pituitary adenoma. Overproduction insulin-like factor-1 (IGF-1) due to GH hypersecretion leads various clinical features characterized somatic overgrowth, physical changes, multiple comorbidities, and increased mortality. The average age at diagnosis 40 50 years, with no se...
conclusions our findings indicated a lower level of both omentin-1 and igf-1 in women with mets; this might play a role in the pathogenesis of mets. furthermore, the main finding of the current investigation was the association between omentin, visfatin and igf-1; however determining the molecular mechanism of the observed relationships needs further studies. results significantly lower levels ...
به منظور بررسی تاثیر شکل فیزیکی خوراک وتغذیه علوفه بر بیان ژن های فاکتور رشد شبه انسولین 1 و 2 (igf-1 و igf-2) در دیواره شکمبه گوساله های شیری هلشتاین آزمایشی با استفاده از 52 راس گوساله نر در قالب طرح کاملا تصادفی با چهار تیمار انجام شد. تیمارهای آزمایشی شامل جیره آغازین آردی، جیره آغازین آجیلی (شامل ذرت و جو بخار داده شده و ورقه ورقه شده)، جیره آغازین پلت و جیره آغازین آردی به همراه 10 درصد ی...
the insulin-like growth factor i receptor (igf-ir) plays an essential role in the establishment and maintenance of transformed phenotype. interference with the igf-ir pathway by antisense causes reversal of the transformed phenotype in many rodent and human tumor cell lines. we stably transfected the pc-3 human prostate cancer cell line with an igf-ir antisense rna expression plasmid. the numbe...
Abstract Introduction: There is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. Insulin receptors hybridize with insulin like growth factor receptor (IGF-I) to transduce the signals in different areas of the brain. In this article we aimed at investigating whether the expression of IGF-I receptor and IGF-I binding proteins (IGFBP1) is change...
The insulin-like growth factor I receptor (IGF-IR) plays an essential role in the establishment and maintenance of transformed phenotype. Interference with the IGF-IR pathway by antisense causes reversal of the transformed phenotype in many rodent and human tumor cell lines. We stably transfected the PC-3 human prostate cancer cell line with an IGF-IR antisense RNA expression plasmid. The ...
This experiment was designed to study the effect of insulin like growth factor-I (IGF-I) on cryopreservation of Hariana bull semen. For this purpose, semen ejaculates were collected from four Hariana bulls using artificial vagina at biweekly interval. The semen samples which possess more than 70% initial progressive motility and above 500 million/mL spermatozoa concentration was subsequently su...
Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are the most important regulators of growth, regeneration metabolism. The influence GH IGF-1 on pediatric liver transplant outcomes is mediated through body weight regulation, specific effects hepatocyte function immune system activity. In recent years, blood levels these factors life expectancy, both in healthy individuals recipients...
Introduction: In recent years, a number of researches have been carried out regarding the relationship between atherosclerosis and serum levels of GH and IGF-1 and different results were obtained. This study aimed to determine the effect of a six-month aerobic exercise on levels of GH, IGF-1 and GH/IGF-1 ratio serum in sedentary middle-aged women Methods: Nineteen healthy females, who were sel...
Background & Objective: To find an association between gene variants of insulin-like growth factor-1 (IGF-1) and 5,10-methylenetetrahydrofolate reductase (MTHFR) with the risk of acne vulgaris (AV). Methods: In a case-control study, we investigated 150 AV patients and 148 healthy individuals (aged 18-25 years) for the IGF-1 G>A and MTHFR C677T polymorphis...
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