BACKGROUND Workers in modern office buildings frequently have unexplained work-related symptoms or combinations of symptoms. We assessed whether ultraviolet germicidal irradiation (UVGI) of drip pans and cooling coils within ventilation systems of office buildings would reduce microbial contamination, and thus occupants' work-related symptoms. METHODS We undertook a double blind, multiple cro...

Public health concerns such as multi- and extensive drug-resistant tuberculosis, bioterrorism, pandemic influenza, and severe acute respiratory syndrome have intensified efforts to prevent transmission of infections that are completely or partially airborne using environmental controls. One such control, ultraviolet germicidal irradiation (UVGI), has received renewed interest after decades of u...

Experimental systems have been built in laboratories worldwide to investigate the influence of various environmental parameters on the efficacy of UV germicidal irradiation (UVGI) for deactivating airborne microorganisms. It is generally recognized that data from different laboratories might vary significantly due to differences in systems and experimental conditions. In this study we looked at...

In-duct ultraviolet germicidal irradiation (UVGI) systems treat moving air streams in heating, ventilation, and air-conditioning (HVAC) systems to inactivate airborne microorganisms. UVGI system performance depends on air temperature, velocity, cumulative operating time, variations in exposure time and other factors. Annual simulations of UVGI efficiency and space concentration that accounted f...

Ultraviolet germicidal irradiation (UVGI) is increasingly used in health care facilities to kill airborne bacteria and control the spread of airborne infection among occupants. The most widely used form of UVGI is the passive upper-room lamps that generate a horizontal layer irradiance field above the occupied zone. In this study, the efficacy of killing airborne bacteria by upper-room UVGI in ...

Several approaches for the inactivation of bacteriophage lambda, including UV germicidal irradiation (UVGI) and the chemical agents Virkon-S, Chloros, Decon-90, and sodium hydroxide (NaOH), were compared. Virkon, NaOH, and UVGI caused a ≥7-log(10) reduction in phage titers. This study successfully describes several methods with potential for bacteriophage inactivation in industrial settings.