cDNA encoding the 20-kD subunit of coatomer, zeta-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to zeta-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (beta-, beta'-, gamma-...

Styers ML, O’Connor AK, Grabski R, Cormet-Boyaka E, Sztul E. Depletion of -COP reveals a role for COP-I in compartmentalization of secretory compartments and in biosynthetic transport of caveolin-1. Am J Physiol Cell Physiol 294: C1485–C1498, 2008. First published April 2, 2008; doi:10.1152/ajpcell.00010.2008.—We have utilized small interfering RNA (siRNA)-mediated depletion of the -COP subunit...

We compared postural control of expert gymnasts (G) to that of non-gymnasts (NG) during bipedal closed-eyes quiet standing using conventional and nonlinear dynamical measures of center of foot pressure (COP) trajectories. Earlier findings based on COP classical variables showed that gymnasts exhibited a better control of postural balance but only in demanding stances. We examined whether the ef...

Cops and Robbers is a vertex-pursuit game played on graphs which has received much recent attention. Graphs where one cop has a winning strategy, so-called cop-win graphs, were discovered in the early 1980’s by Nowakowski and Winkler and independently by Quilliot. Since their introduction, the structure of cop-win graphs has been relatively well-understood. Cop-win graphs possess a vertex elimi...

UNLABELLED The need to develop new dental luting agents in order to improve the success of treatments has greatly motivated research. OBJECTIVE The aim of this study was to evaluate the diametral tensile strength (DTS) and film thickness (FT) of an experimental dental luting agent derived from castor oil (COP) with or without addition of different quantities of filler (calcium carbonate - CaC...

We explored changes in the postural preparation to stepping introduced by modifications of the initial coordinates of the center of pressure (COP). We hypothesized that the postural adjustments in the anterior-posterior direction would persist across all initial COP manipulations while the adjustments in the medio-lateral direction would be highly sensitive to the initial COP coordinate. Health...

Two new pyrene-cored covalent organic polymers (COPs), CK-COP-1 and CK-COP-2, were synthesized via the one-step polymerization of two thiophene-based isomers, 1,3,6,8-tetra(thiophene-2-yl) pyrene (L1 ) and 1,3,6,8-tetra(thiophene-3-yl) pyrene (L2 ). The resulting pyrene-cored COPs exhibit rather different surface areas of 54 m2 g-1 and 615 m2g-1 for CK-COP-1 and CK-COP-2, respectively. The CO2 ...

The role of a facilitator is key to the effective establishment and sustainment of Communities of Practice (COP). This paper presents a taxonomy of facilitation tasks that have to be carried out to support various COP processes that take place during the different stages in a COP’s life-cycle. Inspired by facilitation research in the area of Group Support Systems (GSS), we identified 33 facilit...