In this paper we present a model for estimation of the C-terminal tubulin tail (CTT) dynamics in cytoskeletal microtubules of nerve cells. We show that the screened Coulomb interaction between a target CTT and the negatively charged microtubule surface as well as its immediate CTT neighbours results in confinement of the CTT motion within a restricted volume referred to as a thermal cone. Withi...

Substantial controversy surrounds the membrane topology of the HIV-1 gp41 C-terminal tail (CTT). While few studies have been designed to directly address the topology of the CTT, results from envelope (Env) protein trafficking studies suggest that the CTT sequence is cytoplasmically localized, as interactions with intracellular binding partners are required for proper Env targeting. However, pr...

OBJECTIVES To determine the utility of the cell transfer technique (CTT) for BRAF molecular testing on thyroid fine-needle aspiration (FNA) specimens. METHODS Polymerase chain reaction (PCR)-based BRAF molecular testing was performed on tissues obtained through CTT from both air-dried and ethanol-fixed direct smears of thyroid FNA specimens and then compared with the corresponding thyroidecto...

Introduction: Whole breast radiotherapy after breast-conserving surgery decrease the risk of local recurrence. this study investigates the dosimetric aspects of intensity modulated radiotherapy (IMRT) compared to conventional tangential wedge-based beams techniques (CTT) of the whole breast in early stages breast cancer patients.   Materials and Methods: Co...

Cystic trophoblastic tumor (CTT) is a rare testicular germ cell tumor (GCT) predominantly seen in post-chemotherapy patients. It is prognostically similar to teratoma and requires no additional chemotherapy in the absence of a nonteratomatous GCT component. We report a case of metastatic CTT in a patient with primary testicular teratoma without prior chemotherapy. Retroperitoneal lymph node met...

Objectives: To determine the utility of the cell transfer technique (CTT) for the BRAF molecular testing on thyroid fine-needle aspirates (FNA). Methods: Polymerase chain reaction (PCR)based BRAF molecular testing was performed on tissues obtained through CTT from both airdried and ethanol-fixed direct smears of thyroid FNA, and then compared with the corresponding thyroidectomy formalin-fixed,...

This paper describes a treatment-outcome study of Cognitive Trauma Therapy for Battered Women (CTT-BW) with PTSD. Derived from psychological learning principles, CTT-BW emphasizes the role of irrational beliefs and evaluative language in chronic PTSD. CTT-BW includes trauma history exploration, PTSD psychoeducation, stress management, psychoeducation about dysfunctional self-talk and self-monit...

the classical test theory (ctt) and item response theory (irt) are widely used in construction and analysis of exams and questionnaires. because of the various shortcomings of ctt, irt has been designed. even though irt has overcome most of the limitations of ctt and has made computer adaptive testing possible, it is still important to point out that not enough reasons exist to totally discard ...