The data on the protective properties of Prunella grandiflora L. extract were obtained when used together with anticancer drug etoposide experimental strain Drosophila melanogaster . combined use and 10% P. decreased mortality in D. individuals to 15% doubled average individual fertility compared this cytostatic without extract. Using SMART method, presence antigenotoxic effect was identified, ...

Abstract Background Various bleaching agents are used in food industries among which some reacts to form alloxan. Therefore, the alloxan can indirectly enter a human body and thus an important aspects for studying its effect on development. In present study, of was studied climbing ability, pupation emergence flies. Fifty first instar larvae were introduced separately vials containing 0.001, 0....

Las homeoproteínas dirigen el desarrollo embrionario de los organismos mediante la unión del homeodominio al DNA y su interacción con otras proteínas. Antennapedia (Antp) se encarga formar patas alas en tórax e interactúa TFIIEβ a través D. melanogaster. En este trabajo mostramos que únicamente dos aminoácidos Antp son necesarios para formación patas. La función estas interacciones contribuye c...

One general approach for assessing whether phenotypic variation is due to selection is to test its correlation with presumably neutral molecular variation. Neutral variation is determined by population history, the most likely alternative explanation of spatial genetic structure, whereas phenotypic variation may be influenced by the spatial pattern of selection pressure. Several methods for com...

To contribute to our general understanding of the evolutionary forces that shape variation in genome sequences in nature, we have sequenced genomes from 50 isofemale lines and six pooled samples from populations of Drosophila melanogaster on three continents. Analysis of raw and reference-mapped reads indicates the quality of these genomic sequence data is very high. Comparison of the predicted...

Drosophila melanogaster is widely used as a model in DNA variation studies. Patterns of polymorphism have, however, been affected by the history of this species, which is thought to have recently spread out of Africa to the rest of the world. We analyzed DNA sequence variation in 11 populations, including four continental African and seven non-African samples (including Madagascar), at four ind...

Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness d...

In the Materials and Methods section, primer sequences for quantitative RT-PCR of the CCHa2 gene are incorrect; the correct sequences are as follows. access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Considerable evidence indicates an obligate partnership of the Drosophila melanogaster Vestigial (VG) and Scalloped (SD) proteins within the context of wing development. These two proteins interact physically and a 56-amino-acid motif within VG is necessary and sufficient for this binding. While the importance of this SD-binding domain has been clearly demonstrated both in vitro and in vivo, th...