BACKGROUND The invasion of first trimester extravillous trophoblast (EVT) to decidua is an important event in placentation. Leukemia inhibitory factor (LIF) is an essential factor for mouse implantation, and it is reported that LIF may be involved in human first trimester EVT invasion. Prostaglandin E2 (PGE2) is also known as a critical factor for first trimester EVT invasion. In this study, we...

Extravillus trophoblast (EVT) invasion plays a critical role in placental development. Integrins bind to extracellular matrix (ECM) proteins to mediate EVT cell adhesion, migration, and invasion. Changes in O-glycans on β1-integrin have been found to regulate cancer cell behavior. We hypothesize that O-glycosyltransferases can regulate EVT invasion through modulating the glycosylation and funct...

Background: Recent advances in endovascular therapy (EVT) have increased its utility in the management of peripheral artery disease. We assessed long-term outcomes after EVT versus bypass surgery for superficial femoral artery (SFA) lesions. Methods: Revascularization procedures for SFA lesions were performed in 107 limbs (52 limbs undergoing bypass surgery and 55 limbs undergoing EVT) at our f...

BACKGROUND Extravillous trophoblast (EVT) cells are of pivotal importance in human embryo implantation and homeostasis of the maternal fetal interface. Invasion of the endometrium by EVT contributes to placental anchorage, spiral artery remodeling, immunological defense, tolerogenic responses, and several collaborative cross talks involved in establishing and maintaining a successful pregnancy....

BACKGROUND AND PURPOSE Endovascular treatment (EVT) is a new standard of care for selected, large vessel occlusive strokes. We aimed to determine frequency of potentially eligible patients for intravenous thrombolysis (IVT) and EVT in comprehensive stroke centers. In addition, predictors of EVT eligibility were derived. METHODS Patients from a stroke center-based registry (2003-2014), admitte...

Results Sample size: 88 patients. Repair treatment: surgical(S) 28,41%, endovascular (EVT) 56,82% and conservative 14,77%. Morbidity-GOS scale (S/EVT): 1 = 8 % /14 %; 2 = 4 %/ 2%; 3 =12 % /12 % 4: 28%/ 14% 5: 48 %/ 58% (p 0,59). We separated 2 GOS groups: good prognosis (grade 3,4,5) 88 %/84% and bad prognosis (1,2) 12 %/16% (p 0,64). Complications (S/EVT): vasospasm 28% /22% (p 0,57); rebleedi...

BACKGROUND AND PURPOSE AICA aneurysms are rare and a challenge to treat surgically. We present our experience of the angiographic results and the clinical outcomes for 9 AICA aneurysms treated by EVT. MATERIALS AND METHODS Between 1997 and 2009, EVT was attempted for 9 AICA aneurysms. Six patients presented with SAH, and 3 aneurysms were found incidentally. The location of the aneurysms was t...

PURPOSE To examine the validity of the Expressive Vocabulary Test (EVT; K. Williams, 1997) for assessing the expressive vocabulary skills of African American students. METHOD/RESULTS One hundred sixty-five African American preschool and kindergarten students were administered the EVT. The mean EVT score for these African American students was 96.44 (SD = 11.42), which is not appreciably lower...

A contributing factor to poor placental perfusion, leading to intrauterine growth restriction and preeclampsia, is the failure of invading extravillous trophoblast (EVT) cells to remodel the maternal uterine arteries during the first and second trimesters of pregnancy. Noninvasive assessment of EVT cells in ongoing pregnancies is possible beginning three weeks after conception, using trophoblas...

INTRODUCTION Our purpose was to evaluate the safety and efficacy of endovascular treatment (EVT) of stroke caused by large vessel occlusions (LVO) performed by general interventional radiologists in cooperation with stroke neurologists and neuroradiologists at a center with a limited annual number of procedures. We aimed to compare our results with those previously reported from larger stroke c...