The information acquisition of road traffic flow is requisite for urban traffic control and management. Floating car data (FCD) is emerging technique for traffic flow collection of urban large-scale road network, and it can provide effective means to model and analyze road traffic conditions. Map-matching is one of the key techniques for FCD. The typical navigation map-matching algorithms are n...

Rationale: MRI has allowed the recognition of focal cortical dysplasia (FCD) in an increasing number of patients. The precise delineation of FCD is important since freedom from seizures after surgery is closely related to the extent of resection of the pathological tissue. FCD lesions are difficult to delineate on MRI due to their ill-defined boundaries and the complexity of the cortex. We prev...

High-resolution MRI of the brain has made it possible to identify focal cortical dysplasia (FCD) in an increasing number of patients. There is evidence for structural abnormalities extending beyond the visually identified FCD lesion. Voxel-based morphometry (VBM) has the potential of detecting both lesions and extra-lesional abnormalities because it performs a whole brain voxel-wise comparison....

The negatively charged proteoglycans (PG) provide compressive resistance to articular cartilage by means of their fixed charge density (FCD) and high osmotic pressure (π(PG)), and the collagen network (CN) provides the restraining forces to counterbalance π(PG). Our objectives in this work were to: 1), account for collagen intrafibrillar water when transforming biochemical measurements into a F...

Floating car data (FCD) recorded with the Global Positioning System (GPS) are an important data source for traffic research. However, FCD are subject to error, which can relate either to the accuracy of the recordings (measurement error) or to the temporal rate at which the data are sampled (interpolation error). Both errors affect movement parameters derived from the FCD, such as speed or dire...

Evolution repeatedly converges on only a few regulatory circuit designs that achieve a given function. This simplicity helps us understand biological networks. However, why so few circuits are rediscovered by evolution is unclear. We address this question for the case of fold-change detection (FCD): a response to relative changes of input rather than absolute changes. Two types of FCD circuits ...

Focal cortical dysplasia (FCD) likely results from abnormal migration of neural progenitor cells originating from the subventricular zone. To elucidate the roles in molecules that are involved in neural migration pathway abnormalities in FCDs, we investigated the expression patterns of transient receptor potential canonical channel 6 (TRPC6) and brain-derived neurotrophic factor (BDNF) in corti...

Functional brain imaging has revealed two types of dynamic patterns of brain in the resting-state: the dynamics of spontaneous brain activities and the dynamics of functional interconnections between spontaneous brain activities. Although these two types of brain dynamics are usually investigated separately in the literature, recent functional magnetic resonance imaging (fMRI) studies have show...

Parkinson's disease (PD) can be classified into tremor-dominant and akinetic-rigid subtypes, each of which exhibits a unique clinical course and prognosis. The neural basis for these disparate manifestations is not well-understood, however. This study comprehensively investigated the altered functional connectivity patterns of these two subtypes. Twenty-five tremor-dominant patients, 25 akineti...