Glycycoumarin (GCM) is a representative of bioactive coumarin compounds isolated from licorice, an edible and medicinal plant widely used for treating various diseases including liver diseases. The purpose of the present study is to examine the possibility of GCM as a sensitizer to improve the efficacy of BH3 mimetic ABT-737 against liver cancer. Three liver cancer cell lines (HepG2, Huh-7 and ...

Today’s business applications are increasingly process driven, meaning that the main application logic is executed by a dedicate process engine. In addition, component-oriented software development has been attracting attention for building complex distributed applications. In this paper we present the experiences gained from building a process-driven biometric identification application which ...

We propose a new evaluation method for ‘generalized confidential modulation (GCM)’ for quantum communication. Confidential modulation realizes a secret communication by using secret information for modulation and noise in a channel. Y-00 is one of the famous methods of GCM for quantum communication. The existing evaluation methods for GCM are based on stream ciphers. They can estimate its analy...

[1] Both the Colorado State University (CSU) and Goddard superparameterization GCM (SP-GCM) simulate a superactive Asian summer monsoon with unrealistically enhanced levels of precipitation. The underlying physical mechanism for this monsoon bias in the CSU SP-GCM is shown to involve an enhanced convection-wind-evaporation feedback. The feedback process is studied using two experiments with dif...

In flies, the choice between neuronal and glial fates depends on the asymmetric division of multipotent precursors, the neuroglioblast of the central nervous system and the IIb precursor of the sensory organ lineage. In the central nervous system, the choice between the two fates requires asymmetric distribution of the glial cell deficient/glial cell missing (glide/gcm) RNA in the neuroglioblas...

Following an architecture vision such as the Generic Component Model (GCM) architecture framework, health information systems for supporting personalized care have to be based on a component-oriented architecture. Representing concepts and their interrelations, the GCM perspectives system architecture, domains, and development process can be described by the domains' ontologies. The paper intro...

Recently, Niels Ferguson submitted comments to NIST detailing an attack on GCM message authentication when authentication tags are truncated [3]. This work underscores the risks of using GCM with very short tags, and highlights the need for guidance on tag length. However, it does not violate the claims of GCM’s security analysis [4], nor does it present any weakness that was not described in t...

Neuronal chloride concentration ([Cl(-)](i)) is known to be dynamically modulated and alterations in Cl(-) homeostasis may occur in the brain at physiological and pathological conditions, being also likely involved in glioma-related seizures. However, the mechanism leading to changes in neuronal [Cl(-)](i) during glioma invasion are still unclear. To characterize the potential effect of glioma ...

This memo describes the use of the Advanced Encryption Standard (AES) in Galois/Counter Mode (GCM) as a Transport Layer Security (TLS) authenticated encryption operation. GCM provides both confidentiality and data origin authentication, can be efficiently implemented in hardware for speeds of 10 gigabits per second and above, and is also well-suited to software implementations. This memo define...

Globally coupled map (GCM) model can evolve through chaotic searching into several stable periodic orbits under properly controlled parameters. This can be exploited in information processing such as associative memory and optimization. In this paper, we propose a novel covariance learning rule for multivalue patterns and apply it in memorization of gray-scale images based on modified GCM model...